2-(4-(Difluoromethyl)-6-(4-fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid CAS 937607-14-2
| CAS No. | 937607-14-2 |
| Molecular Formula | C16H12F3N3O2 |
| Molecular Weight | 335.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-(Difluoromethyl)-6-(4-fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid.
2-(4-(Difluoromethyl)-6-(4-fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937607-14-2), molecular formula C16H12F3N3O2 and molecular weight 335.28 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-(Difluoromethyl)-6-(4-fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (C16H12F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-(Difluoromethyl)-6-(4-fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3O2 |
| Molecular Weight | 335.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoromethyl Standards
- 2-(4-(Difluoromethyl)-6-(1,3-dimethyl-1h-pyrazol-4-yl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 1006444-98-9)
- 2-[4-(difluoromethyl)-6-(1,5-dimethyl-1h-pyrazol-4-yl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1006477-98-0)
- Ethyl 2-(4-(difluoromethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1011373-83-3)
- Ethyl 7-(difluoromethyl)-5-(p-tolyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 738603-08-2)
- 6-(Difluoromethyl)-3-methoxy-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (CAS 2173070-92-1)
- 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-carbonyl chloride (CAS 1804428-49-6)
- 4-(Difluoromethyl)-6-fluoro-2-iodonicotinoyl chloride (CAS 1804706-48-6)
- 2-(Difluoromethyl)-3-fluoro-6-iodopyridine-5-carbonyl chloride (CAS 1805045-39-9)
Recommended Standards
- 2-((Tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid (CAS 301196-85-0)
- 2-{2-[3-(trifluoromethyl)phenoxy]ethyl}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 321432-39-7)
- 1-((1-(3-(Trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)oxy)propan-2-one (CAS 34580-66-0)
- 4-(((4-(Trifluoromethoxy)phenyl)amino)methyl)phthalazin-1(2H)-one (CAS 305368-11-0)
- Docosa-4,8,12,15,19-pentaenoic acid (CAS 2548-85-8)
- 1-Fluoro-7-methoxynaphthalen-2-ol (CAS 1447449-99-1)
- 4-Chloro-5H,6H,7H,8H,9H-pyrimido[4,5-d]azepine (CAS 1057338-28-9)
- Cesium Trifluoroacetate (CAS 21907-50-6)
- Benzyl ((1-(2-aminoacetyl)piperidin-4-yl)methyl)(cyclopropyl)carbamate (CAS 1353984-67-4)
- 1-(2,2-Difluoroethyl)-3-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazole (CAS 1856025-55-2)
- 1-(Pyridin-2-yl)ethan-1-amine; oxalic acid (CAS 1197232-85-1)
- 3-((3,5-Dichloropyridin-2-yl)amino)piperidin-2-one (CAS 1248594-31-1)
- Tert-butyl (S)-2-(aminomethyl)-5-oxopyrrolidine-1-carboxylate (CAS 1632227-96-3)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
Why CATO?
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