(E)-3-(3-Bromo-5-methoxy-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)phenyl)acrylic acid CAS 938018-54-3
| CAS No. | 938018-54-3 |
| Molecular Formula | C19H15BrF3NO5 |
| Molecular Weight | 474.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (E)-3-(3-Bromo-5-methoxy-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)phenyl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(E)-3-(3-Bromo-5-methoxy-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)phenyl)acrylic acid (CAS 938018-54-3) is a high-purity analytical reference standard with the molecular formula C19H15BrF3NO5 and a molecular weight of 474.23 g/mol.
The molecular framework of (E)-3-(3-Bromo-5-methoxy-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)phenyl)acrylic acid (C19H15BrF3NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H15BrF3NO5 |
| Molecular Weight | 474.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related E Standards
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- (4-Bromo-3-hydroxy-2-naphthoato)(8-quinolinolato)copper (CAS 14039-99-7)
- (2E)-3-[(4-Bromo-3-methylphenyl)amino]-1-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}prop-2-en-1-one (CAS 477888-57-6)
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- 7-Bromo-2-chloro-5-trityl-5H-pyrrolo[2,3-b]pyrazine (CAS 1509941-36-9)
Recommended Standards
- P7C3, 98% (CAS 301353-96-8)
- Ambroxol Impurity 13 (CAS 305867-38-3)
- 2,2’-Dibromo-9,9’-spirobifluorene (CAS 67665-47-8)
- 1-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 956627-68-2)
- N-((5-Fluorothiophen-2-yl)methyl)-5-(methoxymethyl)-1-methyl-1H-pyrazol-3-amine hydrochloride (CAS 1856063-90-5)
- Ethyl ((1H-imidazol-2-yl)methyl)carbamate (CAS 518036-06-1)
- N-(1H-benzo[d]imidazol-2-yl)thiophene-3-carboxamide (CAS 55842-48-3)
- N-(2-(aminomethyl)pyridin-4-yl)acetamide hydrochloride (CAS 1824097-80-4)
- 5-Bromo-3-phenylisoxazole (CAS 3356-92-1)
- Bicalutamide EP Impurity F (CAS CATO-C4X-101326)
- 5-Methyl-2-(trifluoromethyl)thiazole-4-carboxylic acid (CAS 1564582-05-3)
- 5-(4-Chlorophenyl)-2-((4-methoxyphenyl)thio)nicotinonitrile (CAS 338954-94-2)
- 2-amino-N-[4-(2H-1,2,3-triazol-2-yl)phenyl]acetamide hydrochloride (CAS 1240527-83-6)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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