1-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid CAS 956627-68-2
| CAS No. | 956627-68-2 |
| Molecular Formula | C18H8Cl2F3N3O3S |
| Molecular Weight | 474.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid.
1-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 956627-68-2), molecular formula C18H8Cl2F3N3O3S and molecular weight 474.24 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H8Cl2F3N3O3S, 1-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 474.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H8Cl2F3N3O3S |
| Molecular Weight | 474.24 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related dichlorophenyl Standards
- Ethyl 5-[(2,4-dichlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-triazine-6-carboxylate (CAS 338957-02-1)
- Ethyl 5-(2,4-dichlorophenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-1H-pyrrole-3-carboxylate (CAS 338396-55-7)
- 2-((4-(2,4-Dichlorophenyl)-5-((naphthalen-1-ylamino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1306738-78-2)
- 1-(2,6-Dichlorophenyl)-6-(4-(2-hydroxyethoxy)benzyl)-3-isopropyl-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 784211-09-2)
- 3-(2,4-Dichlorophenyl)-N-(3,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 400075-14-1)
- N-{1-[(3,4-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}-1-{[3-(trifluoromethyl)phenyl]sulfanyl}formamide (CAS 338783-87-2)
- 2,4-Dichlorophenyl 2-(4-bromophenyl)quinoline-4-carboxylate (CAS 355433-82-8)
- 1-(3,4-Dichlorophenyl)-3-(4-fluorophenyl)-5-(2,3,4-trimethoxyphenyl)-4,5-dihydro-1H-pyrazole (CAS 329778-82-7)
Recommended Standards
- Ambroxol Impurity 13 (CAS 305867-38-3)
- 5-Ethylcarboxamido-2-iodo-2-3-O-isopropylideneadenosine (CAS 162936-24-5)
- (E)-3-(3-Bromo-5-methoxy-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)phenyl)acrylic acid (CAS 938018-54-3)
- (E)-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(((2-(4-chlorophenyl)-2-cyanoethylidene)amino)oxy)acetamide (CAS 303151-69-1)
- N2,N2,N4,N4-tetramethylpyrimidine-2,4-diamine (CAS 1076-94-4)
- 1-(Bicyclo[1.1.1]pentan-1-yl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 2714373-46-1)
- rac-3-Tert-Butyl-5-(7-Ethyl-2-Benzofuranyl)-2-oxazolidinone (CAS 1076199-68-2)
- 1-Bromo-2-methylpropane-d9 (CAS 1080497-35-3)
- 4-Fluoro-2,6-dimethoxybenzaldehyde (CAS 139549-11-4)
- Apixaban Impurity 103 (CAS CATO-C4X-1088103)
- 0554AD 1185304-81-7 2-Benzyl-2,3-dihydro-1H-isoindol-5-ylaminedihydrochloride C15H18Cl2N2 (CAS 1185304-81-7)
- 3-(Azepan-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane (CAS 1559047-91-4)
- 2-Ethynyl-4-(trifluoromethyl)thiazole (CAS 1432496-79-1)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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