4-((2-Chloro-6-fluorobenzyl)oxy)-3-ethoxybenzoic acid CAS 938375-84-9
| CAS No. | 938375-84-9 |
| Molecular Formula | C16H14ClFO4 |
| Molecular Weight | 324.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 324.73 g/mol gives 4-((2-Chloro-6-fluorobenzyl)oxy)-3-ethoxybenzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-((2-Chloro-6-fluorobenzyl)oxy)-3-ethoxybenzoic acid (CAS 938375-84-9), molecular formula C16H14ClFO4 and molecular weight 324.73 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-((2-Chloro-6-fluorobenzyl)oxy)-3-ethoxybenzoic acid (C16H14ClFO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((2-Chloro-6-fluorobenzyl)oxy)-3-ethoxybenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClFO4 |
| Molecular Weight | 324.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-((2-Chloro-4-fluorobenzyl)oxy)-3-ethoxybenzoic acid (CAS 1142201-95-3)
- 4-((2-Chloro-4-fluorobenzyl)oxy)-3-methoxybenzohydrazide (CAS 1706445-09-1)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3-methoxypropyl)propanamide (CAS 339099-94-4)
- 5-(3-Chloro-2-fluorobenzyl)-2,4-dimethoxybenzoic Acid (CAS 949465-79-6)
- Methyl 3-(2-chloro-6-fluorophenyl)-5-(2-(dimethylamino)vinyl)isoxazole-4-carboxylate (CAS 338417-50-8)
- (E)-2-((2-chloro-4-fluorobenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-32-8)
- (E)-2-((2-chloro-6-fluorobenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-38-4)
- 2-(8-Chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7h-purin-7-yl)ethane-1-sulfonyl fluoride (CAS 877964-18-6)
Recommended Standards
- 1-Phenylpentadecane-d36 (CAS 352431-31-3)
- N-(5-((5-Chlorothiophen-2-yl)methyl)-1,3,4-oxadiazol-2-yl)-5-methylisoxazole-3-carboxamide (CAS 1020978-13-5)
- Methyl (E)-3-(2-chloro-6-fluorophenyl)-5-(2-(dimethylamino)vinyl)isoxazole-4-carboxylate (CAS 1391943-72-8)
- Dihydralazine Impurity 6 (CAS CATO-C4X-20786)
- 1-(2-Hydroxyethyl)-5-methyl-1H-benzo[d]imidazole-2-carboxylic acid (CAS 883542-66-3)
- 2-(dimethyl-4H-1,2,4-triazol-3-yl)ethan-1-amine dihydrochloride (CAS 1797933-01-7)
- 5-(4-Fluorophenyl)-7-methyl-1,3,4,5-tetrahydro-2h-benzo[e][1,4]diazepin-2-one (CAS 1023558-43-1)
- Vilanterol Impurity 81 (CAS CATO-C4X-193581)
- 1-(Tert-butyl) 2-methyl 1H-pyrrolo[3,2-c]pyridine-1,2-dicarboxylate (CAS 1330755-10-6)
- 5-(Aminomethyl)-N-butyl-N-methyl-2-pyridinamine (CAS 1016510-29-4)
- (3-(3-(Furan-2-yl)-1,2,4-oxadiazol-5-yl)azetidin-1-yl)(pyridin-2-yl)methanone (CAS 1428349-52-3)
- 3-Chloro-2-(2,2,2-trifluoroethoxy)pyridine (CAS 1355068-59-5)
- n-(3-Hydroxypropyl)methanesulfonamide (CAS 52177-30-7)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
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