2-chloro-N-[(4-chlorophenyl)methyl]quinazolin-4-amine CAS 938524-91-5

Description

Compared with other compounds in its class, the molecular weight of 304.17 g/mol gives 2-chloro-N-[(4-chlorophenyl)methyl]quinazolin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-chloro-N-[(4-chlorophenyl)methyl]quinazolin-4-amine (CAS 938524-91-5), molecular formula C15H11Cl2N3 and molecular weight 304.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-chloro-N-[(4-chlorophenyl)methyl]quinazolin-4-amine (C15H11Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-chloro-N-[(4-chlorophenyl)methyl]quinazolin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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