3-amino-6-(difluoromethyl)-4-phenylthieno[2,3-b]pyridine-2-carbonitrile CAS 942358-04-5
| CAS No. | 942358-04-5 |
| Molecular Formula | C15H9F2N3S |
| Molecular Weight | 301.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-amino-6-(difluoromethyl)-4-phenylthieno[2,3-b]pyridine-2-carbonitrile.
3-amino-6-(difluoromethyl)-4-phenylthieno[2,3-b]pyridine-2-carbonitrile (CAS 942358-04-5), molecular formula C15H9F2N3S and molecular weight 301.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-amino-6-(difluoromethyl)-4-phenylthieno[2,3-b]pyridine-2-carbonitrile (C15H9F2N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-amino-6-(difluoromethyl)-4-phenylthieno[2,3-b]pyridine-2-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9F2N3S |
| Molecular Weight | 301.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 3-[(4-fluorophenyl)sulfamoyl]thiophene-2-carboxylic acid (CAS 944893-98-5)
- rac Enterolactone -13C3 (CAS 918502-72-4)
- 5-(4-Fluorophenyl)isoxazole (CAS 138716-37-7)
- 3-bromo-1-(4-methylphenyl)pyrrolidin-2-one (CAS 1282220-90-9)
- 1-(Chloromethyl)-3H-naphtho[2,1-b]pyran-3-one (CAS 41295-62-9)
- 3-(3-Chlorophenyl)-1-propylamine (CAS 18655-49-7)
- 6-((3,5-Dimethylphenyl)selanyl)-1-((2-hydroxyethoxy)methyl)-5-isopropylpyrimidine-2,4(1H,3H)-dione (CAS 172255-88-8)
- 2-(3-tert-Butyl-4-methoxymethoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (CAS 1442430-86-5)
- 5-methyl-1-[2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)propyl]-1H-pyrazol-3-amine (CAS 1174880-95-5)
- 2,4-Dichloro-5-ethyl-6-methylpyrimidine (CAS 861033-35-4)
- 3-(Benzhydryloxy)piperidine (CAS 78503-38-5)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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