1-[2-Chloro-4-(methylsulfonyl)phenyl]piperidine-3-carboxylic acid CAS 942474-35-3
| CAS No. | 942474-35-3 |
| Molecular Formula | C13H16ClNO4S |
| Molecular Weight | 317.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-[2-Chloro-4-(methylsulfonyl)phenyl]piperidine-3-carboxylic acid (C13H16ClNO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-[2-Chloro-4-(methylsulfonyl)phenyl]piperidine-3-carboxylic acid (CAS 942474-35-3) is a high-purity analytical reference standard with the molecular formula C13H16ClNO4S and a molecular weight of 317.79 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16ClNO4S |
| Molecular Weight | 317.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(4-chloro-2-fluorophenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023531-97-6)
- N-(2-Chloro-4-fluorophenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023867-57-3)
- 3-Chloro-6-methoxy-N-phenylbenzo[b]thiophene-2-carboxamide (CAS 113424-98-9)
- 1-[2-Chloro-5-methyl-4-(methylsulfonyl)phenyl]-pyrrolidine-2-carboxylic acid (CAS 1188371-30-3)
- (3S)-1-(3-Chloro-2-methylbenzenesulfonyl)piperidine-3-carboxylic acid (CAS 1212582-76-7)
- ((4-Chloro-2,5-dimethylphenyl)sulfonyl)-l-proline (CAS 345637-80-1)
- (2-Chloro-4-fluorophenyl)(3-(pyrrolidin-1-ylmethyl)phenyl)methanone (CAS 898770-70-2)
- (3-Chloro-5-fluorophenyl)(3-(pyrrolidin-1-ylmethyl)phenyl)methanone (CAS 898770-72-4)
Recommended Standards
- 1-[(4-Methoxyphenyl)sulfonyl]piperidine-4-carbonyl chloride (CAS 941867-62-5)
- 2-((1H-Benzo[d]imidazol-2-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 41215-89-8)
- 1-(2-Chloro-4-(methylsulfonyl)phenyl)piperidine-4-carboxylic acid (CAS 942474-34-2)
- 2-((2-Chlorobenzyl)thio)-8-methyl-4H-pyrido[1,2-a][1,3,5]triazin-4-one (CAS 896336-87-1)
- Bis(pyridine)cobalt (CAS 20710-54-7)
- 4-(2-Furanyl)-1,2,5,6,7,8-hexahydro-2-thioxo-3-quinolinecarbonitrile (CAS 83989-90-6)
- N-[2-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl]acetamide (CAS 1697657-82-1)
- (Z)-Hex-1-en-1-ylboronic acid (CAS 54354-55-1)
- 5-Phenylisoindoline-1,3-dione (CAS 2021-26-3)
- 3-Chloro-N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N',2,2-trimethylpropanehydrazide (CAS 303985-96-8)
- (2R,3R,4S,5R)-2-(6-Amino-2-(3-methoxyprop-1-yn-1-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 137896-14-1)
- 2-Chloro-7-methoxy-4-(trifluoromethyl)quinoline (CAS 852062-05-6)
- 7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl Paclitaxel (CAS 156413-61-5)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com