4-[(2-Fluorophenoxy)methyl]benzoic acid CAS 943114-74-7
| CAS No. | 943114-74-7 |
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-[(2-Fluorophenoxy)methyl]benzoic acid (CAS 943114-74-7) is a high-purity analytical reference standard with the molecular formula C14H11FO3 and a molecular weight of 246.23 g/mol.
4-[(2-Fluorophenoxy)methyl]benzoic acid (C14H11FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-[(2-Fluorophenoxy)methyl]benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluorophenoxy Standards
- 2-(3-Fluorophenoxy)-2-phenylacetic acid (CAS 1016520-75-4)
- 3-[(3-Fluorophenoxy)methyl]benzoic acid (CAS 1019462-57-7)
- 2-[(3-Fluorophenoxy)methyl]benzoic Acid (CAS 114312-47-9)
- 2-[(2-Fluorophenoxy)methyl]benzoic acid (CAS 1156944-71-6)
- 4-((4-Fluorophenoxy)methyl)benzoic acid (CAS 149288-44-8)
- 2-[(4-Fluorophenoxy)methyl]benzoic acid (CAS 198565-84-3)
- 3-[(2-Fluorophenoxy)methyl]benzoic acid (CAS 944891-81-0)
- 3-[(4-fluorophenoxy)methyl]benzoic acid (CAS 869950-21-0)
Recommended Standards
- 4-(Morpholin-4-yl)-2-(trifluoromethyl)aniline (CAS 78335-26-9)
- 4'-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 865186-68-1)
- 4-(Hydrazinecarbonyl)-N-(pyridin-4-yl)-1H-imidazole-5-carboxamide (CAS 627470-11-5)
- 4'-Fluoro-5-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 916343-83-4)
- N-Mesityl-2-(methylthio)nicotinamide (CAS 1007768-20-8)
- N-(3-Fluorophenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477331-47-8)
- 4'-Fluoro-2-methoxy-4-(trifluoromethyl)biphenyl (CAS 1214367-21-1)
- 2-(2-(((Benzyloxy)carbonyl)amino)ethyl)thiazole-4-carboxylic acid (CAS 1513232-20-6)
- 2-Amino-3-iodo-5-(trifluoromethyl)benzonitrile (CAS 1221792-71-7)
- 3-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-oxoethyl)-5-methyl-5-phenylimidazolidine-2,4-dione (CAS 956263-04-0)
- Cyclopentyl(2-(morpholinomethyl)phenyl)methanone (CAS 898751-37-6)
- 2-(4-BOC-AMINO-PHENYL)-1,3-PROPANEDIOL (CAS 954124-35-7)
- 4-(5-Oxo-4,5-dihydropyrazin-2-yl)benzoic acid (CAS 98377-47-0)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
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