4'-Fluoro-5-methoxy-[1,1'-biphenyl]-3-carboxylic acid CAS 916343-83-4
| CAS No. | 916343-83-4 |
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4'-Fluoro-5-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 916343-83-4), molecular formula C14H11FO3 and molecular weight 246.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4'-Fluoro-5-methoxy-[1,1'-biphenyl]-3-carboxylic acid (C14H11FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4'-Fluoro-5-methoxy-[1,1'-biphenyl]-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 3'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 106291-25-2)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1178021-58-3)
- 2-Fluoro-5-(2-methoxyphenyl)benzoic acid (CAS 1178303-59-7)
- 2-Fluoro-4-(3-methoxyphenyl)benzoic acid (CAS 1178418-69-3)
- 4-Fluoro-3-(3-methoxyphenyl)benzoic acid (CAS 1181452-19-6)
- 4-Fluoro-3-(2-methoxyphenyl)benzoic acid (CAS 1181639-56-4)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1182754-74-0)
- 2-Fluoro-4-(4-methoxyphenyl)benzoic acid (CAS 1183759-96-7)
Recommended Standards
- 4'-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 865186-68-1)
- 4-Methyl-2-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine (CAS 869950-20-9)
- 4-[(2-Fluorophenoxy)methyl]benzoic acid (CAS 943114-74-7)
- 5-Nitro-N4-(pyridin-3-ylmethyl)pyrimidine-4,6-diamine (CAS 450344-92-0)
- 9-Chloro-N-(2-morpholinoethyl)acridine-4-carboxamide (CAS 646072-61-9)
- 2,5-Diethyl-6-methylthieno[2,3-d]pyrimidine-4-thiol (CAS 917747-85-4)
- 1-(2-Chloropyrimidin-4-yl)pyrrolidin-3-amine (CAS 945895-41-0)
- (S)-2-Methyl-5-(pyrrolidin-2-yl)pyridine (CAS 77629-50-6)
- 5-Amino-1-(3,5-dimethylphenyl)-1H-pyrazole-4-carboxamide (CAS 1006597-08-5)
- 6-(Thiomorpholinosulfonyl)quinazoline-2,4-diamine (CAS 56044-16-7)
- (5Z)-3-Ethyl-5-[(4-methoxyphenyl)methylidene]-2-[(4H-1,2,4-triazol-4-yl)imino]-1,3-thiazolidin-4-one (CAS 478258-91-2)
- 4-(4-Bromophenyl)but-3-en-1-amine (CAS 1181412-49-6)
- 2-Amino-6-(methylthio)pyrimidine-4-carboxylic acid (CAS 7249-72-1)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
Why CATO?
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