1-(2-Chlorobenzyl)-3-[4-(1,1-dichloro-2,2-difluoro-ethoxy)phenyl]urea CAS 94336-05-7
| CAS No. | 94336-05-7 |
| Molecular Formula | C16H13Cl3F2N2O2 |
| Molecular Weight | 409.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(2-Chlorobenzyl)-3-[4-(1,1-dichloro-2,2-difluoro-ethoxy)phenyl]urea (CAS 94336-05-7) is a high-purity analytical reference standard with the molecular formula C16H13Cl3F2N2O2 and a molecular weight of 409.64 g/mol.
1-(2-Chlorobenzyl)-3-[4-(1,1-dichloro-2,2-difluoro-ethoxy)phenyl]urea (C16H13Cl3F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-(2-Chlorobenzyl)-3-[4-(1,1-dichloro-2,2-difluoro-ethoxy)phenyl]urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl3F2N2O2 |
| Molecular Weight | 409.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzyl Standards
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- (5-((4-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl acetate (CAS 318469-50-0)
- 7-(4-Chlorobenzyl)-3-(4-methoxybenzyl)-8-methyl-2,3,4,9-tetrahydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one (CAS 1374509-74-6)
- 2,6-Bis((2-chlorobenzyl)thio)pyrimidin-4-amine (CAS 6299-26-9)
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Recommended Standards
- ((3S,7aS)-3-(((tert-Butyldiphenylsilyl)oxy)methyl)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (CAS 2763159-59-5)
- rel-((3R,7aR)-3-(((tert-Butyldiphenylsilyl)oxy)methyl)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (CAS 2763159-58-4)
- ((3S,7aR)-3-(((tert-Butyldiphenylsilyl)oxy)methyl)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (CAS 2763160-17-2)
- rel-((3R,7aS)-3-(((tert-Butyldiphenylsilyl)oxy)methyl)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (CAS 2763160-15-0)
- 4-Methyl-5-(trifluoromethyl)benzene-1,2-diamine (CAS 1737-64-0)
- 3-Deoxyaconitine (CAS 3175-95-9)
- 2-(3-aminoazetidin-1-yl)ethan-1-ol (CAS 1409292-18-7)
- 5-Fapyguanine (CAS 51093-31-3)
- 2-(3-Hydroxy-2,2-dimethylpropoxy)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2490666-02-7)
- Methyl 4-hydroxy-1,4-dihydropyrimidine-5-carboxylate (CAS 758641-87-1)
- 3-Hydroxy-4-morpholinotetrahydrothiophene 1,1-dioxide (CAS 53381-43-4)
- methyl 2-fluoro-2-(2-methoxy-4-pyridyl)propanoate (CAS 2755892-82-9)
- 2-Cyclopropoxy-4-methoxyaniline (CAS 1243394-48-0)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
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