2,4,6-Tribromo-3,5-difluorobenzonitrile CAS 943528-40-3
| CAS No. | 943528-40-3 |
| Molecular Formula | C7Br3F2N |
| Molecular Weight | 375.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,4,6-Tribromo-3,5-difluorobenzonitrile (CAS 943528-40-3), a certified reference material (molecular formula C7Br3F2N, MW 375.79 g/mol) for analytical method development and quality control.
The molecular framework of 2,4,6-Tribromo-3,5-difluorobenzonitrile (C7Br3F2N) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7Br3F2N |
| Molecular Weight | 375.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Tribromo Standards
- 2,4,6-Tribromo-3-nitrophenol (CAS 69076-62-6)
- 1,3,5-tribromo-2,4-dimethoxybenzene (CAS 25676-73-7)
- 2,4,6-Tribromo-3-nitroaniline (CAS 62406-72-8)
- 3,4,5-Tribromo-6-cyano (1H)indazole (CAS 1000342-54-0)
- 1,2,3-Tribromo-5-(tert-butyl)benzene (CAS 114895-17-9)
- 3,3,5-Tribromo--2-oxo-7-azaindoline (CAS 183208-32-4)
- 2,3,6-Tribromo(difluoromethoxy)benzene (CAS 1261269-96-8)
- 1,2,4-Tribromo-5-(difluoromethoxy)benzene (CAS 1261650-61-6)
Recommended Standards
- 2-((4-Chlorobenzyl)sulfinyl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339097-86-8)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(2-methoxyphenyl)thiourea (CAS 326815-44-5)
- 2-(4-Chloro-3-nitrophenyl)-1H-imidazo[4,5-b]phenazine (CAS 303059-17-8)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}phenyl)-3-ethylurea (CAS 338407-35-5)
- Methyl 4-(2-aminoethyl)benzoate (CAS 77265-67-9)
- (1S,3s)-3-((tert-butyldimethylsilyl)oxy)cyclobutane-1-carboxylic acid (CAS 1431285-80-1)
- 2-Amino-6-(difluoromethyl)-3-iodopyridine-4-sulfonamide (CAS 1804680-33-8)
- Daptomycin Impurity 8 (CAS CATO-C4X-13788)
- 4-Bromo-3-hydroxypicolinic acid (CAS 349471-65-4)
- 3-Oxo-2,3-dihydrobenzofuran-2-carbaldehyde (CAS 63136-73-2)
- 4-Nitronaphthalene-1-acetic Acid (CAS 89278-25-1)
- Bicalutamide Impurity 30 (CAS CATO-C4X-101330)
- Loxoprofen Impurity 16 Sodium salt (CAS CATO-C4X-148816)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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