2-(4-Iodophenyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 944580-94-3
| CAS No. | 944580-94-3 |
| Molecular Formula | C14H8F3IN2 |
| Molecular Weight | 388.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(4-Iodophenyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 944580-94-3) is a high-purity analytical reference standard with the molecular formula C14H8F3IN2 and a molecular weight of 388.13 g/mol.
The molecular framework of 2-(4-Iodophenyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridine (C14H8F3IN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8F3IN2 |
| Molecular Weight | 388.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Iodophenyl Standards
- (4-Iodophenyl)diphenylphosphane (CAS 440111-10-4)
- 1-Boc-4-(4-Iodophenyl)piperazine (CAS 151978-66-4)
- Ethyl 8-(2-iodophenyl)-8-oxooctanoate (CAS 898777-21-4)
- Ethyl 8-(3-iodophenyl)-8-oxooctanoate (CAS 898777-36-1)
- Ethyl 8-(4-iodophenyl)-8-oxooctanoate (CAS 898777-48-5)
- (S)-3-(4-Iodophenyl)-2-(2,2,2-trifluoroacetamido)propanoic acid (CAS 115820-04-7)
- N-(2-Iodophenyl)-4-methoxybenzenesulfonamide (CAS 346689-84-7)
- N-(4-Iodophenyl)-4-methoxybenzenesulfonamide (CAS 314054-03-0)
Recommended Standards
- 7-Iodo-1-phenyl-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 159724-30-8)
- 6-Iodo-2-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine (CAS 478040-61-8)
- Uranyl Acetate (Oxyacetate Uranium) (CAS 541-09-3)
- Carbidopa Impurity 30 (CAS CATO-C4X-231030)
- 4-(6-Benzyl-2-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)morpholine (CAS 1170226-53-5)
- 4-Chloro-5-methyl-2-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 68143-24-8)
- 2,2,3,3,3-pentafluoropropane-1-sulfonyl chloride (CAS 1210498-48-8)
- Salbutamol Impurity 71 (CAS 232590-81-7)
- 5-ethyl-4-phenyl-2,3-dihydro-1,3-thiazol-2-one (CAS 1095051-83-4)
- (2-Phenylethynyl)(tricyclohexylphosphine)gold (CAS 49788-63-8)
- 3-Chloro-4,6-dimethylpyridazine (CAS 17258-26-3)
- 4-Fluoro-a-methylbenzylisothiocyanate (CAS 182565-27-1)
- 1-Phenyl-2-(pyridin-4-yl)ethanone (CAS 1620-55-9)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
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