4-(3-Bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol CAS 945376-95-4

Purity 97%+In StockPharmaceutical Standards
CAS No.945376-95-4
Molecular FormulaC12H8BrN3O
Molecular Weight290.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(3-Bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol CAS 945376-95-4 chemical structure

Description

The occurrence of 4-(3-Bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(3-Bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol (CAS 945376-95-4), molecular formula C12H8BrN3O and molecular weight 290.12 g/mol, is a CATO reference standard with documented purity and traceability.

4-(3-Bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol (C12H8BrN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H8BrN3O
Molecular Weight290.12 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentBr-containing
Nitrogen Atoms3

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