3,4-Difluoro-alpha-(trifluoromethyl)benzyl Alcohol CAS 945978-37-0
| CAS No. | 945978-37-0 |
| Molecular Formula | C8H5F5O |
| Molecular Weight | 212.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H5F5O, 3,4-Difluoro-alpha-(trifluoromethyl)benzyl Alcohol contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 212.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3,4-Difluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 945978-37-0) is a high-purity analytical reference standard with the molecular formula C8H5F5O and a molecular weight of 212.12 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5F5O |
| Molecular Weight | 212.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,3-Difluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1343223-64-2)
- 1,3-Difluoro-4-methyl-2-(trifluoromethoxy)benzene (CAS 1404194-46-2)
- 2,3-Difluoro-1-methyl-4-(trifluoromethoxy)benzene (CAS 1404194-74-6)
- (3,5-Difluoro-4-(trifluoromethyl)phenyl)methanol (CAS 1417567-87-3)
- 3,5-Difluoro-4-trifluoromethylanisole (CAS 1429056-37-0)
- (2,4-Difluoro-3-(trifluoromethyl)phenyl)methanol (CAS 1445995-77-6)
- 1,3-Difluoro-4-methoxy-2-(trifluoromethyl)benzene (CAS 1799420-90-8)
- (2,6-Difluoro-3-(trifluoromethyl)phenyl)methanol (CAS 1800231-22-4)
Recommended Standards
- 3-(Pentafluoroethyl)phenol (CAS 53998-04-2)
- 3,5-Difluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 923690-98-6)
- 2-Hydroxy-3,5-dinitrobenzaldehyde (CAS 2460-59-5)
- 3,5-Dinitro-4-hydroxybenzaldehyde (CAS 52132-61-3)
- 3-Methyl-4-(phenylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 478031-97-9)
- 1-(4-Amino-3-methylpiperidin-1-yl)ethan-1-one (CAS 1228453-25-5)
- (S)-S-Benzoylcaptopril (CAS 75107-57-2)
- Ozenoxacin Impurity 73 (CAS CATO-C4X-279673)
- Ethyl 3,4,6-Tri-O-acetyl-2-acetamido-2-deoxy-α-D- thioglucopyranoside (CAS 49810-41-5)
- 3-(Difluoromethoxy)cyclohexan-1-one (CAS 2285099-77-4)
- N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 (CAS 2107273-80-1)
- Apalutamide Impurity 80 (CAS CATO-C4X-274980)
- 2-Chloro-N-(2-chloroethyl)aniline (CAS 64086-71-1)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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