Metaraminol Impurity 63 CAS 946-80-5
| CAS No. | 946-80-5 |
| Molecular Formula | C13H12O |
| Molecular Weight | 184.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metaraminol Impurity 63.
Metaraminol Impurity 63 (CAS 946-80-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12O and a molecular weight of 184.23 g/mol.
The molecular framework of Metaraminol Impurity 63 (C13H12O) is characterized by a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Metaraminol Impurity 63 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12O |
| Molecular Weight | 184.23 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Metaraminol Standards
- Metaraminol Impurity 5 (CAS 20727-99-5)
- Metaraminol impurity 104 (CAS 1379208-51-1)
- Metaraminol impound 105 (CAS CATO-C4X-2252105)
- Metaraminol Impurity 39 (CAS CATO-C4X-225239)
- Metaraminol Impurity 78 (CAS 65133-68-8)
- Metaraminol Impurity 87 (CAS CATO-C4X-225287)
- Metaraminol Impurity 86 (CAS 1824725-09-8)
- Metaraminol Impurity 11 (CAS 871875-57-9)
Recommended Standards
- Dimenhydrinate EP Impurity I (CAS 91-01-0)
- Propylparaben-d4 (CAS 1219802-67-1)
- 4-Biphenylmethanol (CAS 3597-91-9)
- 4-Benzylphenol (CAS 101-53-1)
- Guaifenesin Impurity 5 (CAS 2049-21-0)
- Anagrelide Impurity 28 Methanesulfonate (CAS 752151-24-9（free base）)
- Pimavanserin Impurity 9 (CAS CATO-C4X-19389)
- 4-(4-Bromo-1h-pyrazol-1-yl)butan-1-amine (CAS 1184468-64-1)
- 1'-(Tert-butoxycarbonyl)spiro[chromene-2,4'-piperidine]-4-carboxylic acid (CAS 1160247-75-5)
- Methyl 3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate (CAS 251096-53-4)
- 1-(3-Fluoro-2-methylbenzyl)piperidin-4-amine dihydrochloride (CAS 1286272-70-5)
- Formaldehyde, polymer with 1-phenylethanone (CAS 25398-55-4)
- N-Methyl Viloxazine (CAS 48173-47-3)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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