1-{3-[(4-Methylphenyl)methyl]-1,2,4-thiadiazol-5-yl}piperazine CAS 946419-02-9
| CAS No. | 946419-02-9 |
| Molecular Formula | C14H18N4S |
| Molecular Weight | 274.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-{3-[(4-Methylphenyl)methyl]-1,2,4-thiadiazol-5-yl}piperazine (CAS 946419-02-9) is a high-purity analytical reference standard with the molecular formula C14H18N4S and a molecular weight of 274.38 g/mol.
The molecular framework of 1-{3-[(4-Methylphenyl)methyl]-1,2,4-thiadiazol-5-yl}piperazine (C14H18N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-{3-[(4-Methylphenyl)methyl]-1,2,4-thiadiazol-5-yl}piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18N4S |
| Molecular Weight | 274.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methylphenyl Standards
- 1-{3-[(3-Methylphenyl)methyl]-1,2,4-thiadiazol-5-yl}piperazine (CAS 1029718-77-1)
- 4-(4-Methylphenyl)-5-(piperidin-1-yl)-4h-1,2,4-triazole-3-thiol (CAS 848369-54-0)
- 3-(3-Methylphenyl)-2-sulfanylidene-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1154244-40-2)
- 3-(2-Methylphenyl)-2-sulfanylidene-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 688354-32-7)
- (3Z)-3-[(3-Methylphenyl)imino]-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indol-2-one (CAS 477886-41-2)
- 2-(3-methylphenyl)-1,3-thiazole-4-sulfonyl chloride (CAS 1269152-70-6)
- 3-(3-Methylphenyl)-3-(2,2,2-trifluoroacetamido)propanoic acid (CAS 117291-12-0)
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Recommended Standards
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- 3＇-MethoxyPuerarin (CAS 117047-07-1)
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- Semaglutide impurity 40 (CAS CATO-C4X-222640)
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