3-Chloro-4-(3,4-difluorophenoxy)aniline CAS 946775-44-6
| CAS No. | 946775-44-6 |
| Molecular Formula | C12H8ClF2NO |
| Molecular Weight | 255.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 3-Chloro-4-(3,4-difluorophenoxy)aniline (C12H8ClF2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 255.65 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3-Chloro-4-(3,4-difluorophenoxy)aniline (CAS 946775-44-6), a certified reference material (molecular formula C12H8ClF2NO, MW 255.65 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8ClF2NO |
| Molecular Weight | 255.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Methyl 2-(6-chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)acetate (CAS 104662-84-2)
- 4-(3-Chloro-2-fluorophenoxy)-3-fluoroaniline (CAS 1206593-32-9)
- (7-Chloro-5-oxo-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl)acetic acid (CAS 1243086-72-7)
- Methyl 6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylate (CAS 141761-83-3)
- 2-(7-Chloro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetic acid (CAS 1510338-58-5)
- (R)-2-(3-Chloro-2-hydroxypropoxy)isoindoline-1,3-dione (CAS 338786-76-8)
- (S)-2-(3-Chloro-2-hydroxypropoxy)isoindoline-1,3-dione (CAS 272447-40-2)
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Recommended Standards
- 3-Chloro-4-(2,4-difluorophenoxy)aniline (CAS 946662-64-2)
- 3-Chloro-4-(cyanomethoxy)-5-ethoxybenzoic acid (CAS 713103-75-4)
- 3-Chloro-2-(3,4-difluorophenoxy)aniline (CAS 946682-44-6)
- 4-(4-Chlorophenoxy)-3,5-difluoroaniline (CAS 549547-33-3)
- Methyl 4-hydroxy-5-oxo-1-(pyridin-2-ylmethyl)-2,5-dihydro-1H-pyrrole-3-carboxylate (CAS 885951-47-3)
- (3,5-Dimethoxyphenyl)(6-methylpyridin-3-yl)methanone (CAS 1187167-92-5)
- (4,4-Difluoro-1-(pyridin-4-ylmethyl)cyclohexyl)methanamine dihydrochloride (CAS 1989793-11-4)
- Ethyl 2-nitrophenylacetate, 97% (CAS 31912-02-4)
- 5-Hydroxypyridin-2(1H)-one (CAS 5154-01-8)
- 2-Bromo-4-(difluoromethyl)-3-methylpyridine (CAS 1805300-11-1)
- 1-(3-Bromo-5-fluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 2090695-67-1)
- 1-(1-Ethyl-1h-pyrazol-4-yl)-6-oxopiperidine-3-carboxylic acid (CAS 1458375-54-6)
- 2-(6-Bromo-3-(difluoromethyl)-5-fluoropyridin-2-yl)acetonitrile (CAS 1805397-82-3)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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