8-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridine CAS 947533-47-3

Description

Compared with other compounds in its class, the molecular weight of 291.12 g/mol gives 8-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

8-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridine (CAS 947533-47-3), molecular formula C13H8BrFN2 and molecular weight 291.12 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 8-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridine (C13H8BrFN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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