1-Bromo-2-{[2-(trifluoromethoxy)phenoxy]methyl}benzene CAS 947534-45-4
| CAS No. | 947534-45-4 |
| Molecular Formula | C14H10BrF3O2 |
| Molecular Weight | 347.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 347.13 g/mol gives 1-Bromo-2-{[2-(trifluoromethoxy)phenoxy]methyl}benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Bromo-2-{[2-(trifluoromethoxy)phenoxy]methyl}benzene (CAS 947534-45-4) is a high-purity analytical reference standard with the molecular formula C14H10BrF3O2 and a molecular weight of 347.13 g/mol.
Based on its molecular formula C14H10BrF3O2, 1-Bromo-2-{[2-(trifluoromethoxy)phenoxy]methyl}benzene contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10BrF3O2 |
| Molecular Weight | 347.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-4-((4-(trifluoromethoxy)phenoxy)methyl)benzene (CAS 1312077-91-0)
- 1-Bromo-3-((4-(trifluoromethoxy)phenoxy)methyl)benzene (CAS 1710125-81-7)
- n-(2-Bromo-4-sulfamoylphenyl)-2,2,2-trifluoroacetamide (CAS 1283449-68-2)
- [2-Bromo-4-(trifluoromethyl)phenyl](4-fluorophenyl)methanone (CAS 85721-09-1)
- 6'-Bromo-4,4-difluoro-8'-methyl-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione (CAS 1849592-64-8)
- 2-(5-Bromo-2-methoxybenzylidene)-6-hydroxybenzofuran-3(2h)-one (CAS 620545-86-0)
- 3-(6-Bromo-2H-naphtho[1,8-cd]isoxazol-2-yl)piperidine-2,6-dione (CAS 2767588-62-3)
- 3-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine-6-carboxylic acid (CAS 866145-46-2)
Recommended Standards
- 1-(Benzyloxy)-4-bromo-2-(trifluoromethoxy)benzene (CAS 647856-30-2)
- 4-Benzyloxy-1-bromo-2-trifluoromethoxybenzene (CAS 647856-28-8)
- Cobalt(II)-EDTA (CAS 14931-83-0)
- 2-(Benzyloxy-1-bromo-4-(trifluoromethoxy)benzene (CAS 1704065-45-1)
- 1-(1-(4-Chlorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole (CAS 88557-56-6)
- (3aR,6aR)-Hexahydro-2H-thieno[2,3-c]pyrrole 1,1-dioxide (CAS 1486470-59-0)
- Perchlorocoronene (CAS 94227-23-3)
- Methyl 2-({[(4Z)-5-oxo-3-phenyl-4,5-dihydro-1,2-oxazol-4-ylidene]methyl}amino)acetate (CAS 477851-05-1)
- Methyl 2-phenylquinoline-4-carboxylate (CAS 4546-48-9)
- 2-((4-Fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethan-1-amine hydrochloride (CAS 1094398-06-7)
- Eltrombopag Impurity 9 (CAS CATO-C4X-11989)
- Tryptophan Impurity 18 (CAS CATO-C4X-137318)
- n-(4-Aminophenyl)-n-methylethane-1-sulfonamide (CAS 1040070-45-8)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com