Tryptophan Impurity 18 CAS CATO-C4X-137318
| CAS No. | CATO-C4X-137318 |
| Molecular Formula | C26H30N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tryptophan Impurity 18 (CAS CATO-C4X-137318), a pharmacopoeial impurity reference standard (molecular formula C26H30N4O4HCl, MW 499.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Tryptophan Impurity 18 (C26H30N4O4HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Tryptophan Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H30N4O4 HCl |
| Molecular Weight | 499.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Tryptophan Standards
- Tryptophan Impurity 44 (CAS 101948-12-3)
- L-Tryptophan tert-Butyl Ester HCl (CAS 115692-31-4)
- D-Tryptophan-2′,4′,5′,6′,7′-d5 (indole-d5) (CAS 1202359-57-6)
- Tryptophan Metabolite (HIAA-d5) (CAS 1219802-93-3)
- DL-Tryptophan-d8 (CAS 1233395-85-1)
- Tryptophan Impurity 7 (CAS 13081-15-7)
- Tryptophan EP Impurity A (CAS 132685-02-0)
- Tryptophan EP Impurity A 2HCl (CAS 132685-02-0（free base）)
Recommended Standards
- Mavacoxib Impurity 1 (CAS CATO-C4X-30591)
- Fluoxetine Impurity 12 (CAS CATO-C4X-135212)
- Betamethasone impurity 95 (CAS 1815577-58-2)
- (3-Fluoro-4-methylphenyl)(furan-2-yl)methanone (CAS 1248905-66-9)
- 4-Bromo-3-cyano-2-iodobenzoic acid (CAS 1807015-20-8)
- 2-(2,2-Difluoroethoxy)-3-fluorobenzenamine (CAS 1566580-28-6)
- N-((1H-indazol-4-yl)carbamothioyl)benzamide (CAS 54768-43-3)
- Niraparib Impurity 10 (CAS 2091464-38-7)
- Tert-butyl 4-(3,3-diethyl-2-oxoindolin-1-yl)piperidine-1-carboxylate (CAS 1358667-41-0)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com