Cefpodoxime Proxetil EP Impurity H CAS 947692-16-2
| CAS No. | 947692-16-2 |
| Molecular Formula | C42H54N10O18S4 |
| Molecular Weight | 1115.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefpodoxime Proxetil EP Impurity H (CAS 947692-16-2, C42H54N10O18S4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefpodoxime Proxetil EP Impurity H (C42H54N10O18S4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefpodoxime Proxetil EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C42H54N10O18S4 |
| Molecular Weight | 1115.19 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 10 |
| Sulfur Atoms | 4 |
Related Cefpodoxime Standards
- Cefpodoxime Impurity 47 (CAS CATO-C4X-157947)
- Cefpodoxime Proxetil Impurity 35 (CAS CATO-C4X-157935)
- Cefpodoxime Impurity 55 (CAS CATO-C4X-157955)
- Cefpodoxime impurity 70 (CAS CATO-C4X-157970)
- Cefpodoxime Proxetil Impurity 36 (CAS CATO-C4X-157936)
- Cefpodoxime Impurity 65 (CAS CATO-C4X-157965)
- Cefpodoxime Impurity 64 (CAS CATO-C4X-157964)
- Cefpodoxime Impurity 66 (CAS CATO-C4X-157966)
Recommended Standards
- 2,3-Bis(1H,1H,2H,2H-perfluorodecylthio)-1,4-naphthoquinone (CAS 883516-22-1)
- m-PEG24-azide (CAS 2563873-82-3)
- Desmopressin Impurity 49 (CAS CATO-C4X-221549)
- Amoxicillin Impurity 90 (CAS CATO-C4X-114890)
- Papaverine Impurity 45 (CAS CATO-C4X-206745)
- Ilaprazole impurity 203 (CAS 1378653-43-0（free base）)
- Buserelin Impurity 7 (CAS CATO-C4X-22127)
- 4-Hydroxy-3-(3-phenylacryloyl)-2H-chromen-2-one (CAS 209973-90-0)
- 2-(4-(Methylsulfonyl)-2-nitrophenyl)acetic acid (CAS 929000-10-2)
- 3,3'-(Dimethylsilanediyl)bis(propan-1-ol) (CAS 10325-32-3)
- 1-Bromo-2-ethyl-3-iodobenzene (CAS 1344998-09-9)
- Linezolid Impurity 35 (CAS CATO-C4X-107335)
- 4-Bromo-3-nitroquinoline (CAS 1566897-26-4)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com