Cefpodoxime Impurity 66 CAS CATO-C4X-157966
| CAS No. | CATO-C4X-157966 |
| Molecular Formula | C36H42N10O14S4 |
| Molecular Weight | 967.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefpodoxime Impurity 66.
As a process- or degradation-related impurity, Cefpodoxime Impurity 66 (CAS CATO-C4X-157966, C36H42N10O14S4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefpodoxime Impurity 66 (C36H42N10O14S4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C36H42N10O14S4 |
| Molecular Weight | 967.04 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 10 |
| Sulfur Atoms | 4 |
Related Cefpodoxime Standards
- Cefpodoxime Impurity 64 (CAS CATO-C4X-157964)
- Cefpodoxime Impurity 65 (CAS CATO-C4X-157965)
- Cefpodoxime Proxetil Impurity 21 (CAS CATO-C4X-157921)
- Cefpodoxime Proxetil Impurity 34 (CAS CATO-C4X-157934)
- Cefpodoxime impurity 68 (CAS CATO-C4X-157968)
- Cefpodoxime impurity 69 (CAS CATO-C4X-157969)
- Cefpodoxime Proxetil Impurity 26 (CAS CATO-C4X-157926)
- Cefpodoxime Proxetil Impurity 27 (CAS CATO-C4X-157927)
Recommended Standards
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- Dopamine Impurity 16 (CAS 67992-45-4)
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