1-(3-Fluorophenyl)-5-methyl-1h-1,2,4-triazole-3-carboxylic acid CAS 948007-65-6
| CAS No. | 948007-65-6 |
| Molecular Formula | C10H8FN3O2 |
| Molecular Weight | 221.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 1-(3-Fluorophenyl)-5-methyl-1h-1,2,4-triazole-3-carboxylic acid (CAS 948007-65-6), a certified reference material (molecular formula C10H8FN3O2, MW 221.19 g/mol) for analytical method development and quality control.
The molecular framework of 1-(3-Fluorophenyl)-5-methyl-1h-1,2,4-triazole-3-carboxylic acid (C10H8FN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-(3-Fluorophenyl)-5-methyl-1h-1,2,4-triazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8FN3O2 |
| Molecular Weight | 221.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 1-[(3-Fluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1007477-02-2)
- 2-(1-(4-Fluorophenyl)-1H-1,2,3-triazol-5-yl)acetic acid (CAS 1017423-88-9)
- 1-(3-Fluorophenyl)-5-methyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1020046-35-8)
- 1-(4-Fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-62-4)
- 1-(4-Fluorophenyl)-N-hydroxy-1H-1,2,3-triazole-4-carboximidamide (CAS 1255791-09-3)
- 2-(3-Fluorophenyl)-5-methyl-2h-1,2,3-triazole-4-carboxylic acid (CAS 1315368-15-0)
- 1-(2-Fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 887035-85-0)
- 1-[(2-Fluorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 957354-37-9)
Recommended Standards
- 1-(3-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine (CAS 473732-66-0)
- 1-(4-fluorobenzyl)-4-nitro-1H-imidazole (CAS 68019-63-6)
- 1-(3,5-Bis(difluoromethyl)phenyl)ethan-1-amine (CAS 2794934-81-7)
- 1-(4-Fluoro-phenyl)-5-methyl-1H-[1,2,3]triazole-4-carboxylic acid (CAS 887035-89-4)
- 2-(1-(4-Fluorophenyl)-1H-pyrazol-5-yl)pyridine (CAS 1269294-22-5)
- 3-Bromo-5-(trifluoromethoxy)pyridine (CAS 1060815-01-1)
- 2-((1S,2S)-2-(2-methoxyphenyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2066512-89-6)
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