2-Chloro-3-(3-chloropropyl)-7-fluoroquinoline CAS 948290-17-3
| CAS No. | 948290-17-3 |
| Molecular Formula | C12H10Cl2FN |
| Molecular Weight | 258.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-3-(3-chloropropyl)-7-fluoroquinoline (C12H10Cl2FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-Chloro-3-(3-chloropropyl)-7-fluoroquinoline (CAS 948290-17-3), molecular formula C12H10Cl2FN and molecular weight 258.12 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-3-(3-chloropropyl)-7-fluoroquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2FN |
| Molecular Weight | 258.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-3-(3-chloropropyl)-6-fluoroquinoline (CAS 948294-65-3)
- 2-Chloro-N-(2-chlorobenzyl)-N-cyclopropylacetamide (CAS 1092295-05-0)
- 2-Chloro-N-(3-chlorobenzyl)-N-cyclopropylacetamide (CAS 1175651-36-1)
- 2-Chloro-N-(4-chlorobenzyl)-N-cyclopropylacetamide (CAS 1177199-20-0)
- 5-(3-Chloro-4-methoxyphenyl)-2-(chloromethyl)oxazole (CAS 1215990-56-9)
- (E)-5-chloro-3-(4-chlorobut-2-en-1-yl)benzo[d]oxazol-2(3H)-one (CAS 866150-27-8)
- 2-Chloro-N-(3-chloro-4-fluorophenyl)pyrimidin-4-amine (CAS 919200-71-8)
- 2-chloro-3-(chloromethyl)-7-(methylthio)quinoline (CAS 794582-34-6)
Recommended Standards
- 2-Methyl-2H-indazole-4-boronic Acid Pinacol Ester (CAS 885698-95-3)
- 2-Bromo-6,7-dihydrospiro[pyrazolo[5,1-c][1,4]oxazine-4,3'-pyrrolidine] (CAS 2813866-67-8)
- 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 2377692-89-0)
- 2-Bromo-5,5-dimethyl-5,6-dihydro-4H-pyrazolo[1,5-d][1,4]diazepin-7(8H)-one (CAS 2246364-05-4)
- 1-(4-Chlorophenyl)-3-(3-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-98-9)
- N-(2,5-Dimethylphenyl)-3-(2-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-66-4)
- 202326-55-4 Acrylon-13C3 Acrylonitrile-13C3 Acrylonitrile-13C3(stabilized with 35-45 ppm 4-hydroxy anisole (H750015)) Carbacryl-13C3 Cyanoethene-13C3 Cyanoethylene-13C3 Fumigrain-13C3 NSC 6362-13C3 Propenenitrile-13C3 Vinyl Cyanide-13C3 (CAS 202326-55-4)
- 2',3'-Dichloro-[1,1'-biphenyl]-4-carboxylic acid (CAS 7111-63-9)
- 3,5-Dichloro-6-fluoropicolinic acid (CAS 406676-39-9)
- N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-methylpropyl)-4-methylbenzenesulfonamide (CAS 124984-83-4)
- 4-Amino-3-((4-chlorobenzyl)thio)-1,2,4-triazin-5(4H)-one (CAS 869068-63-3)
- 3-Benzyl-4-(phenylamino)-1H-1,2,4-triazol-5(4H)-one (CAS 75989-69-4)
- 2-(pyridin-2-ylmethyl)cyclopentan-1-one (CAS 13640-55-6)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com