2-chloro-3,5,8-trimethylquinoline CAS 948290-41-3
| CAS No. | 948290-41-3 |
| Molecular Formula | C12H12ClN |
| Molecular Weight | 205.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-chloro-3,5,8-trimethylquinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-chloro-3,5,8-trimethylquinoline (CAS 948290-41-3), a certified reference material (molecular formula C12H12ClN, MW 205.68 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H12ClN, 2-chloro-3,5,8-trimethylquinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 205.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN |
| Molecular Weight | 205.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 4-chloro-2-propylquinoline (CAS 100121-90-2)
- 6-Chloro-2,4,8-trimethylquinoline (CAS 105907-08-2)
- 5-Chloro-2,4,8-trimethylquinoline (CAS 105908-43-8)
- 2-Chloro-7-ethyl-3-methylquinoline (CAS 108097-03-6)
- 4-Chloro-6-propylquinoline (CAS 1156602-03-7)
- 2-Chloro-1-(2,6-dimethylmorpholin-4-yl)propan-1-one (CAS 115840-37-4)
- 4-Chloro-2,3,8-trimethylquinoline (CAS 1203-45-8)
- 4-Chloro-2,3,6-trimethylquinoline (CAS 1203-71-0)
Recommended Standards
- 1-Chloro-8-isopropylisoquinoline (CAS 261359-86-8)
- 2-Chloro-3,6,7-trimethylquinoline (CAS 948290-47-9)
- 1-Chloro-6-isopropylisoquinoline (CAS 630422-59-2)
- 2-Chloro-3-ethyl-8-methylquinoline (CAS 917750-56-2)
- [(3-Fluorophenyl)methyl][1-(4-fluorophenyl)propyl]amine (CAS 1039916-93-2)
- Ethyl 5-oxo-2-phenyl-4,5-dihydro-1H-pyrrole-3-carboxylate (CAS 105194-22-7)
- Methyl 4-chloroquinazoline-7-carboxylate (CAS 183322-47-6)
- Methionine EP Impurity D (CAS CATO-C4X-18274)
- Adamantan-2-one oxime (CAS 4500-12-3)
- Methyl 3-amino-3-(2-methoxyphenyl)propanoate (CAS 1009289-77-3)
- 2-amino-3-(1-benzofuran-2-yl)propanoic acid hydrochloride (CAS 206353-28-8)
- Fluticasone Impurity 4 (CAS 105638-31-1)
- 4-Chloro-6-methoxy-7-(2-(2-methoxyethoxy)ethoxy)cinnoline (CAS 197359-53-8)
- Palmitoyl Pentapeptide-4 (CAS 214047-00-4)
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