(E)-3-(4-Fluorobenzylidene)chroman-4-one CAS 948307-89-9

Purity 97%+In StockPharmaceutical Standards
CAS No.948307-89-9
Molecular FormulaC16H11FO2
Molecular Weight254.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-3-(4-Fluorobenzylidene)chroman-4-one CAS 948307-89-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 254.26 g/mol gives (E)-3-(4-Fluorobenzylidene)chroman-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(E)-3-(4-Fluorobenzylidene)chroman-4-one (CAS 948307-89-9), molecular formula C16H11FO2 and molecular weight 254.26 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, (E)-3-(4-Fluorobenzylidene)chroman-4-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (E)-3-(4-Fluorobenzylidene)chroman-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H11FO2
Molecular Weight254.26 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

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