7-Chloro-4-methoxy-1H-indole-3-carboxylic acid CAS 948581-69-9
| CAS No. | 948581-69-9 |
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 225.63 g/mol gives 7-Chloro-4-methoxy-1H-indole-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Chloro-4-methoxy-1H-indole-3-carboxylic acid (CAS 948581-69-9) is a high-purity analytical reference standard with the molecular formula C10H8ClNO3 and a molecular weight of 225.63 g/mol.
7-Chloro-4-methoxy-1H-indole-3-carboxylic acid (C10H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 7-Chloro-4-methoxy-1H-indole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Ethyl 7-chloro-1H-pyrazolo[4,3-B]pyridine-6-carboxylate (CAS 100478-04-4)
- 5-(5-chloro-2-methoxyphenyl)-1,3,4-oxadiazol-2-amine (CAS 1016686-46-6)
- Ethyl 5-chloro-3H-imidazo[4,5-b]pyridine-2-carboxylate (CAS 1044772-75-9)
- Ethyl 2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1060816-62-7)
- ethyl 6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate (CAS 1083181-27-4)
- 5-Chloro-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 112734-83-5)
- Methyl 4-chloro-2-cyano-5-methoxybenzoate (CAS 1138220-78-6)
- Methyl 6-chloro-8-methylimidazo[1,2-b]pyridazine-3-carboxylate (CAS 1150566-87-2)
Recommended Standards
- 7-Chloro-4-methoxy-1H-indole-2-carboxylic acid (CAS 383132-75-0)
- Ethyl 2-(3-chloropyrazin-2-yl)-2-cyanoacetate (CAS 99446-80-7)
- 7-Amino-4-chloro-3-methoxy-1H-isochromen-1-one (CAS 62252-26-0)
- Ethyl 2-chloro-5H-pyrrolo[3,2-d]pyrimidine-6-carboxylate (CAS 2089378-36-7)
- Fmoc-N-Me-D-Phe(4-OMe)-OH (CAS 193086-28-1)
- 2361-59-3 Benzenemethanamine, 3-bromo-N,N-bis(2-chloroethyl)- (9CI) Benzylamine, N,N-bis(2-chloroethyl)-m-bromo- N,N-Bis(2-chloroethyl)-m-bromobenzylamine BRN 2841930 3-Bromo-N,N-bis(2-chloroethyl)benzenemethanamine m-Bromo-DCBA m-Bromo-di-(2-chloroethyl)-benzylamine (CAS 2361-59-3)
- 3-((4-Chloro-2-methylphenoxy)methyl)benzoic acid (CAS 832740-30-4)
- 2-(4-Ethylbenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1004779-49-0)
- 3-(4-Bromo-3-methyl-1h-pyrazol-1-yl)propanehydrazide (CAS 1004644-56-7)
- Methyl(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylmethyl)amine (CAS 643726-03-8)
- 4-(((4,4-Dimethyl-2,6-dioxocyclohexylidene)methyl)amino)-N-(4-methylpyrimidin-2-yl)benzenesulfonamide (CAS 371947-39-6)
- (R)-Morpholine-3-carboxylic acid (CAS 106825-81-4)
- 3-(2,5-Dihydroxy-1H-pyrrol-3-yl)propane-1-sulfonic acid (CAS 754169-88-5)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com