5,7-Dichloro-4-fluoro-1H-indole-3-carboxylic acid CAS 948581-70-2
| CAS No. | 948581-70-2 |
| Molecular Formula | C9H4Cl2FNO2 |
| Molecular Weight | 248.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,7-Dichloro-4-fluoro-1H-indole-3-carboxylic acid.
CATO supplies 5,7-Dichloro-4-fluoro-1H-indole-3-carboxylic acid (CAS 948581-70-2), a certified reference material (molecular formula C9H4Cl2FNO2, MW 248.04 g/mol) for analytical method development and quality control.
5,7-Dichloro-4-fluoro-1H-indole-3-carboxylic acid (C9H4Cl2FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,7-Dichloro-4-fluoro-1H-indole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4Cl2FNO2 |
| Molecular Weight | 248.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 3,3-Dichloro-6-Fluoro-2,4(1H,3H)-Quinolinedione (CAS 778-61-0)
- 4,7-Dichloro-5-fluoro-1H-indole-2-carboxylic acid (CAS 2755782-68-2)
- 4,7-Dichloro-6-fluoro-1H-indole-2-carboxylic acid (CAS 2755783-53-8)
- 5,7-Dichloro-8-fluoro-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one (CAS 2763160-26-3)
- Methyl 2,4-dichloro-3-cyano-5-fluorobenzoate (CAS 220035-64-3)
- N-(2,6-Dichloro-3-cyano-5-fluoropyridin-4-yl)acetamide (CAS 2763160-25-2)
- 3,5-Dichloro-2-(trifluoromethylthio)pyridine (CAS 1204234-58-1)
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Recommended Standards
- 2-Ethoxycarbonyl-7-methylimidazo[1,2-a]pyridine-6-boronic acid (CAS 2377609-52-2)
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- 1-Fluoro-4-(1-iodoethenyl)benzene (CAS 359887-57-3)
- 5-Amino-2-bromo-4-fluorobenzoic Acid Methyl Ester (CAS 1036389-86-2)
- Protoporphyrin nine zinc (2) (CAS 15442-64-5)
- 4-((3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)thiomorpholine (CAS 864754-37-0)
- tert-Butyl 3-nitropropionate (CAS 204919-53-9)
- Methyl 2-oxa-5-azabicyclo[2.2.1]Heptane-4-carboxylate hydrochloride (CAS 2137451-00-2)
- 4-(2,4-Dinitrophenoxy)-3-ethoxy-5-iodobenzaldehyde (CAS 792945-74-5)
- 2-(4-(Difluoromethyl)-5-fluoro-3-methoxypyridin-2-yl)acetic acid (CAS 1807145-50-1)
- 3-Chloro-2-(2,4-dichlorophenyl)-2H-indazole (CAS 88279-17-8)
- Tetrahydrofuran-3-ylmethylhydrazine (CAS 887592-18-9)
- 4-[(5-Chloro-2,3-dihydro-2,2-dimethyl-7-benzofuranyl)methoxy]-2,3-dimethylbenzenepropanoic Acid (CAS 1234844-11-1)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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