(3-Amino-5-chloropyridin-2-yl)boronic acid CAS 948593-64-4
| CAS No. | 948593-64-4 |
| Molecular Formula | C5H6BClN2O2 |
| Molecular Weight | 172.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Amino-5-chloropyridin-2-yl)boronic acid (C5H6BClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(3-Amino-5-chloropyridin-2-yl)boronic acid (CAS 948593-64-4) is a high-purity analytical reference standard with the molecular formula C5H6BClN2O2 and a molecular weight of 172.38 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6BClN2O2 |
| Molecular Weight | 172.38 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- (2-Amino-5-chloropyridin-4-yl)boronic acid (CAS 1222522-34-0)
- (6-Amino-4-chloropyridin-3-yl)boronic acid (CAS 1225228-21-6)
- (6-Amino-2-chloropyridin-3-yl)boronic acid (CAS 1310404-77-3)
- (5-Amino-6-chloropyridin-3-yl)boronic acid (CAS 1354697-94-1)
- (2-Amino-3-chloropyridin-4-yl)boronic acid (CAS 2304748-30-7)
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- (S)-2-amino-N-isopropyl-4-methylpentanamide (CAS 110374-70-4)
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Recommended Standards
- (2-Chloro-4-methylpyrimidin-5-yl)boronic acid (CAS 2225155-62-2)
- (4-Chloro-2-methylpyrimidin-5-yl)boronic acid (CAS 2225174-35-4)
- Methyltripropylsilane 995-24-4 MFCD30184630 SY043386 (CAS 995-24-4)
- tert-butyltriethylsilane (CAS CATO-C3D-4819)
- 4-Fluoro-3-trifluoromethylbenzenethiol (CAS 1208075-20-0)
- Diisopropyl (perfluorophenyl)boronate (CAS 267006-38-2)
- 3-Amino-n-benzyl-4-chloro-n-methylbenzamide (CAS 1016704-57-6)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl 3-(trifluoromethyl)benzoate (CAS 321430-26-6)
- 2,3,4,5,6,6-Hexachlorocyclohexa-2,4-dienone (CAS 21306-21-8)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-(tert-butyl)phenyl)thiophen-2-yl)boronate (CAS 1402233-55-9)
- 1-(4-Cyclohexylphenyl)-2-methylpropan-1-amine (CAS 863668-06-8)
- SF1126 (CAS 936487-67-1)
- Methyl 2-((4-cyano-1-(p-tolyl)-5,6,7,8-tetrahydroisoquinolin-3-yl)thio)acetate (CAS 861209-23-6)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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