(3aR,6aR)-5-Ethoxycarbonyl-1H-hexahydropyrrolo[3,4-b]pyrrole CAS 948846-39-7
| CAS No. | 948846-39-7 |
| Molecular Formula | C9H16N2O2 |
| Molecular Weight | 184.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3aR,6aR)-5-Ethoxycarbonyl-1H-hexahydropyrrolo[3,4-b]pyrrole (CAS 948846-39-7), molecular formula C9H16N2O2 and molecular weight 184.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3aR,6aR)-5-Ethoxycarbonyl-1H-hexahydropyrrolo[3,4-b]pyrrole (C9H16N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H16N2O2 |
| Molecular Weight | 184.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Recommended Standards
- (3-(Pyridin-2-yl)phenyl)methanamine (CAS 859915-26-7)
- (3S,6R)-3-Methyl-6-(2-methylpropyl)piperazine-2,5-dione (CAS 5845-60-3)
- (2-(Pyridin-3-yl)phenyl)methanamine (CAS 859915-27-8)
- (3S,6S)-3-Isobutyl-6-methylpiperazine-2,5-dione (CAS 24676-83-3)
- 2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)-N-(thiazol-2-yl)thiazole-4-carboxamide (CAS 955976-61-1)
- (3-Bromo-2,2-dimethylpropyl)benzene (CAS 56701-49-6)
- [3-(morpholin-4-yl)propyl]thiourea (CAS 111538-46-6)
- N-Nitroso Almonertinib impurity 4 (CAS CATO-C4X-28924)
- 3-(1-Allyl-1H-indol-3-yl)-3-oxopropanenitrile (CAS 1403567-40-7)
- 2,5-Dichloro-1H-indole (CAS 916258-28-1)
- 5-Methylpyrimidine-4-carboxylic Acid (CAS 933683-35-3)
- 2-[(5-bromo-2-fluorophenyl)amino]Butanamide (CAS 1340052-60-9)
- 8-Bromo-6-methyl-3-nitroimidazo[1,2-a]pyridine (CAS 1072944-59-2)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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