4-Fluoro-4-(hydroxymethyl)piperidine CAS 949100-11-2
| CAS No. | 949100-11-2 |
| Molecular Formula | C6H12FNO |
| Molecular Weight | 133.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-Fluoro-4-(hydroxymethyl)piperidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-Fluoro-4-(hydroxymethyl)piperidine (CAS 949100-11-2), molecular formula C6H12FNO and molecular weight 133.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Fluoro-4-(hydroxymethyl)piperidine (C6H12FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H12FNO |
| Molecular Weight | 133.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 6-fluoro-2-methylpyridin-3-ol (CAS 1227577-28-7)
- 3-Fluoro-1-methylpiperidin-4-ol (CAS 1393100-32-7)
- 3-Fluoro-4-methoxypiperidine (CAS 1545253-16-4)
- 3-Fluoro-3-(methoxymethyl)pyrrolidine (CAS 1567070-60-3)
- Cis-3-Fluoro-4-Methylpiperidin-4-Ol (CAS 1612176-91-6)
- 3-Fluoro-4-methylpiperidin-4-ol (CAS 1823539-12-3)
- (3-fluoro-1-methyl-1H-pyrrol-2-yl)methanol (CAS 2167647-52-9)
- (R)-(3-Fluoro-1-methylpyrrolidin-3-yl)methanol (CAS 2368910-33-0)
Recommended Standards
- 4-(2-Fluoroethyl)morpholine (CAS 691905-88-1)
- N,N-Diethyl-2-Fluoroacetamide (CAS 364-92-1)
- 3-(Fluoromethyl)piperidin-3-ol (CAS 2021392-81-2)
- 2-Amino-4-fluorophenol 399-97-3 4-FLUORO-2-AMINOPHENOL 5-FLUORO-2-HYDROXYANILINE AS00224 (CAS 399-97-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com