Topiramate EP Impurity D CAS 950603-46-0
| CAS No. | 950603-46-0 |
| Molecular Formula | C25H39NO15S |
| Molecular Weight | 625.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Topiramate EP Impurity D (CAS 950603-46-0), a pharmacopoeial impurity reference standard (molecular formula C25H39NO15S, MW 625.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Topiramate EP Impurity D is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 625.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H39NO15S |
| Molecular Weight | 625.64 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Topiramate Standards
- Topiramate Impurity 3 (CAS CATO-C4X-17683)
- Topiramate Impurity 33 (CAS CATO-C4X-176833)
- Topiramate EP Impurity B (CAS 876403-98-4)
- Topiramate Impurity 29 (CAS 53209-14-6)
- Topiramate Impurity 31 (CAS CATO-C4X-176831)
- Topiramate Impurity 11 (CAS CATO-C4X-176811)
- Topiramate Impurity 22 (CAS CATO-C4X-176822)
- Topiramate Impurity 32 (CAS CATO-C4X-176832)
Recommended Standards
- Eravacycline impurity 40 (CAS CATO-C4X-293840)
- Benzyl ((S)-4-methyl-1-(((S)-4-methyl-1-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate (CAS 179324-21-1)
- Amoxicillin Impurity 46 (CAS CATO-C4X-114846)
- Relugolix Impurity 113 (CAS CATO-C4X-2429113)
- Olaparib Impurity 92 (CAS CATO-C4X-113592)
- Ozenoxacin Impurity 81 (CAS CATO-C4X-279681)
- Iguratimod Impurity 116 (CAS CATO-C4X-1826116)
- 2-Bromo-4-fluoro-1-naphthaldehyde (CAS 925442-88-2)
- 4-chloro-2-cyclopropyl-1H-Pyrrolo[2,3-b]pyridine (CAS 1014613-52-5)
- 4-(4-Fluorobenzoyl)-N-(2-methoxyethyl)-1H-pyrrole-2-carboxamide (CAS 478078-61-4)
- N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 477872-23-4)
- tert-Butyl (cis-4-(2-hydroxyethyl)cyclohexyl)carbamate (CAS 1069120-19-9)
- Cetylpyridinium Chloride Impurity 2 (CAS CATO-C4X-27872)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
Why CATO?
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