Cinnarizine impurity 01 CAS 95062-18-3
| CAS No. | 95062-18-3 |
| Molecular Formula | C35H35F2N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cinnarizine impurity 01 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Cinnarizine impurity 01 (CAS 95062-18-3, C35H35F2N2Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Cinnarizine impurity 01 (C35H35F2N2Cl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 557.12 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Cinnarizine impurity 01 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H35F2N2 Cl |
| Molecular Weight | 557.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Cinnarizine Standards
- Cinnarizine-D8 (CAS 1185242-27-6)
- Cinnarizine EP Impurity D (CAS 1199751-98-8)
- Cinnarizine EP Impurity D (CAS 1415587-79-9)
- Cinnarizine Impurity 1 (CAS 16699-20-0)
- Cinnarizine EP Impurity E (CAS 216581-01-0)
- Cinnarizine (CAS 298-57-7)
- Cinnarizine Impurity-E Dihydrochloride (CAS 56265-29-3)
- Cinnarizine EP Impurity B (CAS 750512-44-8)
Recommended Standards
- Levofloxacin Impurity 41 (CAS CATO-C4X-137141)
- Probucol Impurity 1 (CAS 950-59-4)
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- (3-(N,N-Dimethylsulfamoyl)-4-fluorophenyl)boronic acid (CAS 1704121-57-2)
- 4-Bromo-2-chloro-6-(trifluoromethyl)phenyl isothiocyanate (CAS 1027512-61-3)
- N,N-Diethyl-4-methyl-3-nitrobenzenesulfonamide (CAS 91431-22-0)
- 2-[2-(4-Oxopiperidin-1-yl)ethyl]isoindole-1,3-dione (CAS 1484355-05-6)
- 4-Ethyl-5-morpholino-4H-1,2,4-triazole-3-thiol (CAS 847783-74-8)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com