Cinnarizine EP Impurity E CAS 216581-01-0
| CAS No. | 216581-01-0 |
| Molecular Formula | C30H30N2 |
| Molecular Weight | 418.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Cinnarizine EP Impurity E (CAS 216581-01-0, C30H30N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Cinnarizine EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 418.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Cinnarizine EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H30N2 |
| Molecular Weight | 418.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Nitrogen Atoms | 2 |
Related Cinnarizine Standards
- Cinnarizine-D8 (CAS 1185242-27-6)
- Cinnarizine Impurity 1 (CAS 16699-20-0)
- Cinnarizine EP Impurity B (CAS 750512-44-8)
- Cinnarizine (CAS 298-57-7)
- Cinnarizine EP Impurity D (CAS 1415587-79-9)
- Cinnarizine EP Impurity D (CAS 1199751-98-8)
- Cinnarizine EP Impurity C (CAS CATO-C4X-13989)
- Cinnarizine EP Impurity A (CAS 841-77-0)
Recommended Standards
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- Treprostinil Ethyl Ester (CAS 1355990-07-6)
- Apremilast Impurity 38 (CAS 2095036-40-9)
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- Copper-zinc alloy powder, -60 mesh (CAS 63338-02-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com