tert-Butyl 3-(4-fluorophenoxy)pyrrolidine-1-carboxylate CAS 950648-92-7
| CAS No. | 950648-92-7 |
| Molecular Formula | C15H20FNO3 |
| Molecular Weight | 281.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 3-(4-fluorophenoxy)pyrrolidine-1-carboxylate (CAS 950648-92-7) is a high-purity analytical reference standard with the molecular formula C15H20FNO3 and a molecular weight of 281.32 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl 3-(4-fluorophenoxy)pyrrolidine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl 3-(4-fluorophenoxy)pyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20FNO3 |
| Molecular Weight | 281.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-butyl 3-(3-fluorophenyl)morpholine-4-carboxylate (CAS 1989672-80-1)
- Fluvastatin EP Impurity G (CAS 101125-34-2)
- O-Ethyl S-((6-(trifluoromethyl)pyridin-3-yl)methyl) carbonodithioate (CAS 2107987-82-4)
- Sudan Red G-d3 (CAS 1398109-09-5)
- Iron, [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenaminato]](2-)]-, (SP-4-1)- (CAS 71547-22-3)
- 1,7-Heptanediol (CAS 629-30-1)
- Ethyl 1-(difluoromethyl)-3-methyl-1H-pyrazole-5-carboxylate (CAS 128537-24-6)
- tert-Butyl N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-N-methanesulfonylcarbamate (CAS 339105-16-7)
- Amifostine (CAS 20537-88-6)
- 9-methyl-6-azaspiro[3.5]nonan-7-one (CAS 1443980-21-9)
- (3-Fluorophenyl)hydrazine (CAS 658-27-5)
- 2-Amino-5-chloropyridine-3-thiol (CAS 110402-26-1)
- 1-[(4R)-4-(Phenylmethyl)-2-thioxo-3-oxazolidinyl]-1-propanone (CAS 334968-78-4)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com