Ethyl 4-(3-chloro-5-fluorophenyl)-4-oxobutanoate CAS 951889-89-7
| CAS No. | 951889-89-7 |
| Molecular Formula | C12H12ClFO3 |
| Molecular Weight | 258.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-(3-chloro-5-fluorophenyl)-4-oxobutanoate.
Ethyl 4-(3-chloro-5-fluorophenyl)-4-oxobutanoate (CAS 951889-89-7) is a high-purity analytical reference standard with the molecular formula C12H12ClFO3 and a molecular weight of 258.67 g/mol.
The molecular framework of Ethyl 4-(3-chloro-5-fluorophenyl)-4-oxobutanoate (C12H12ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-(3-chloro-5-fluorophenyl)-4-oxobutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClFO3 |
| Molecular Weight | 258.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- 2-Chloro-N-((1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)acetamide (CAS 1216063-07-8)
- Ethyl 4-(3-chloro-2-fluorophenyl)-3-oxobutanoate (CAS 1260896-31-8)
- Methyl 5-(4-chloro-3-fluorophenyl)-5-oxopentanoate (CAS 1443327-33-0)
- Methyl 5-(3-chloro-5-fluorophenyl)-5-oxopentanoate (CAS 1443333-35-4)
- Methyl 5-(3-chloro-4-fluorophenyl)-5-oxopentanoate (CAS 1443344-56-6)
- 7-chloro-6-(trifluoromethyl)quinazolin-4-ol (CAS 1698027-37-0)
- 6-Chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxylic Acid-d3 Methyl Ester (CAS 1795029-57-0)
- 1-[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]methanamine (CAS 900641-14-7)
Recommended Standards
- Ethyl 4-(3-chloro-4-fluorophenyl)-4-oxobutanoate (CAS 951890-03-2)
- Ethyl 4-(4-chloro-2-fluorophenyl)-4-oxobutanoate (CAS 951886-34-3)
- Ethyl 4-(2-chloro-6-fluorophenyl)-4-oxobutanoate (CAS 951887-05-1)
- Ethyl 4-(4-chloro-3-fluorophenyl)-4-oxobutanoate (CAS 473693-78-6)
- 2,6-Bis[(2-hydroxyethyl)amino]toluene (CAS 149330-25-6)
- 5-(4-Chlorophthalazin-1-yl)-N-isopropyl-2-methylbenzenesulfonamide (CAS 732260-56-9)
- 2-Bromo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (CAS 1956325-57-7)
- Dibromopyromellitic Dianhydride (CAS 24848-78-0)
- 1-(3-Fluoro-4-(3-methyl-1h-pyrazol-1-yl)phenyl)ethan-1-one (CAS 1247098-20-9)
- 1-Iodo-3,5-bis(methylsulfonyl)benzene (CAS 849035-96-7)
- 3-{[(Propan-2-yl)amino]methyl}phenol hydrochloride (CAS 1240566-35-1)
- 6-Chloro-N-(2,5-dimethoxyphenyl)quinolin-4-amine (CAS 955315-84-1)
- 1,4-Dioxadispiro[4.1.4(7).3(5)]Tetradecan-12-one (CAS 1702552-21-3)
- Cycloaspeptide A (CAS 109171-13-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com