5-(4-Chlorophthalazin-1-yl)-N-isopropyl-2-methylbenzenesulfonamide CAS 732260-56-9
| CAS No. | 732260-56-9 |
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorophthalazin-1-yl)-N-isopropyl-2-methylbenzenesulfonamide (C18H18ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(4-Chlorophthalazin-1-yl)-N-isopropyl-2-methylbenzenesulfonamide (CAS 732260-56-9) is a high-purity analytical reference standard with the molecular formula C18H18ClN3O2S and a molecular weight of 375.87 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Chlorophthalazin-1-yl)-N-isopropyl-2-methylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophthalazin Standards
- 5-(4-Chlorophthalazin-1-yl)-N-(2-hydroxyethyl)-2-methylbenzenesulfonamide (CAS 733801-91-7)
- 2-(4-(4-Chlorophthalazin-1-yl)phenoxy)-N,N-diethylacetamide (CAS 732260-57-0)
- 5-(4-Chlorophthalazin-1-yl)-N,2-dimethylbenzenesulfonamide (CAS 736940-27-5)
- 6-((4-Chlorophthalazin-1-yl)amino)hexanoic acid (CAS 307514-00-7)
- 4-Benzyl-8-chlorophthalazin-1(2H)-one (CAS 66294-16-4)
- 2-((4-Chlorophthalazin-1-yl)amino)ethan-1-ol (CAS 98911-72-9)
- (1-Chlorophthalazin-6-yl)methanol (CAS 1416713-94-4)
- (1-Chlorophthalazin-6-yl)methanamine (CAS 1416712-76-9)
Recommended Standards
- 5-(4-Chlorobenzamido)-4-cyano-N,N-diethyl-3-methylthiophene-2-carboxamide (CAS 419558-74-0)
- Methyl 2-(4-chlorophenyl)-3-(4-methylbenzoyl)thiazolidine-4-carboxylate (CAS 477768-31-3)
- 5-(4-Chloro-2-methylphenoxymethyl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 748793-44-4)
- N-(2-((4-chlorophenyl)thio)ethyl)-6,7-dimethoxyquinazolin-4-amine (CAS 477859-98-6)
- 2-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-3-methylbutan-1-amine (CAS 1225793-46-3)
- 2-(4-Amino-3-ethylphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol (CAS 637347-78-5)
- 3-(1-Methyl-1H-1,2,4-triazol-3-yl)phenol (CAS 1785074-81-8)
- 2-Chloropyrimidine-4-carboxylic Acid (CAS 149849-92-3)
- Methyl 5-(2-methoxy-2-oxoethyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 303995-96-2)
- Nintedanib Impurity 130 (CAS CATO-C4X-1814130)
- 3-O-tert-Butyldimethylsilyl-D-Erythro-sphingosylphosphorylcholine (CAS 168411-99-2)
- (6-(Dipropylamino)pyridin-3-yl)(phenyl)methanone (CAS 1355223-75-4)
- (2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-phenyl-2-propenamide (CAS 951155-18-3)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
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