N-((5-(4-Fluorophenyl)isoxazol-3-yl)methyl)-2-phenylacetamide CAS 953010-63-4
| CAS No. | 953010-63-4 |
| Molecular Formula | C18H15FN2O2 |
| Molecular Weight | 310.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-((5-(4-Fluorophenyl)isoxazol-3-yl)methyl)-2-phenylacetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-((5-(4-Fluorophenyl)isoxazol-3-yl)methyl)-2-phenylacetamide (CAS 953010-63-4), a certified reference material (molecular formula C18H15FN2O2, MW 310.32 g/mol) for analytical method development and quality control.
The molecular framework of N-((5-(4-Fluorophenyl)isoxazol-3-yl)methyl)-2-phenylacetamide (C18H15FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15FN2O2 |
| Molecular Weight | 310.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-(4-Fluorophenyl)-3-((4-fluorophenyl)sulfonyl)propan-1-one (CAS 477334-49-9)
- 2-(4-Fluorophenyl)-N-((5-phenylisoxazol-3-yl)methyl)acetamide (CAS 946340-21-2)
- N-(4-fluorophenyl)-5-methyl-1-(p-tolyl)-1H-1,2,4-triazole-3-carboxamide (CAS 400080-88-8)
- 3-(4-Fluorophenyl)-6-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 865658-01-1)
- 3-{[(4-fluorophenyl)methyl]sulfanyl}-5H-[1,2,4]triazino[5,6-b]indole (CAS 312278-29-8)
- 4-(2-Fluorophenyl)-2-thioxo-1,2,3,4-tetrahydro-5H-indeno[1,2-d]pyrimidin-5-one (CAS 691873-13-9)
- 4-(4-Fluorophenyl)-5-(1H-indol-3-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 887206-19-1)
- 6-(4-Fluorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CAS 840517-90-0)
Recommended Standards
- 3-(4-Fluorobenzyl)-4-hydroxy-1-(3-pyridinylmethyl)-2(1H)-pyridinone (CAS 477846-00-7)
- N-(2-(Difluoromethoxy)phenyl)-2-(methylthio)nicotinamide (CAS 796059-57-9)
- N'-(2,3-difluorobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 2432855-02-0)
- N'-(2,4-difluorobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 454675-05-9)
- (2-Fluoro-3-nitrophenyl)methanol (CAS 946126-95-0)
- Ethyl 5-isopropoxy-2-methylbenzoate (CAS 2586127-59-3)
- 3,5-Dichloro-2-fluorobenzenesulfonamide (CAS 1806302-27-1)
- Ethyl 4-oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-3-carboxylate (CAS 1420799-97-8)
- 2-(3-Chlorophenyl)-2-iodoacetophenone (CAS 898784-03-7)
- n-(Cyclopropylmethyl)-3-hydroxy-2-naphthamide (CAS 1031947-22-4)
- 2-([1-(3-Methylphenyl)-1h-tetrazol-5-yl]thio)propanoic acid (CAS 917217-91-5)
- (4,6-Dihydroxy-5-(3-(triethoxysilyl)propyl)-1,3-phenylene)bis(phenylmethanone) (CAS 166255-23-8)
- 3-Bromo-N-cyclopropyl-5-(trifluoromethyl)aniline (CAS 1697580-07-6)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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