6-Bromo-2,8-dichloroquinazoline CAS 953039-27-5
| CAS No. | 953039-27-5 |
| Molecular Formula | C8H3BrCl2N2 |
| Molecular Weight | 277.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Bromo-2,8-dichloroquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 6-Bromo-2,8-dichloroquinazoline (CAS 953039-27-5), a certified reference material (molecular formula C8H3BrCl2N2, MW 277.93 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution, 6-Bromo-2,8-dichloroquinazoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 277.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H3BrCl2N2 |
| Molecular Weight | 277.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 8-Bromo-4,6-dichloro-quinazoline (CAS 100948-94-5)
- 6-Bromo-4,8-dichloroquinazoline (CAS 100949-31-3)
- 6-Bromo-2,4-dichloroquinazoline (CAS 102393-82-8)
- 6-Bromo-2,7-dichloroquinazoline (CAS 1036757-08-0)
- 6-Bromo-2,3-dichloroquinoxaline (CAS 108229-82-9)
- 5-Bromo-2,3-dichloroquinoxaline (CAS 1092286-00-4)
- 7-bromo-4,6-dichloroquinazoline (CAS 1260847-61-7)
- 5-Bromo-2,4-dichloroquinazoline (CAS 134517-54-7)
Recommended Standards
- 6-Bromo-1,4-dichlorophthalazine (CAS 240400-95-7)
- 6-Bromo-3,4-dichloro-1,8-naphthyridine (CAS 2074703-23-2)
- 4-Bromo-1,6-dichloro-2,7-naphthyridine (CAS 2385502-17-8)
- 6-Bromo-3,4-dichlorocinnoline (CAS 2065250-59-9)
- 1,7-Dichloroheptan-4-one (CAS 40624-07-5)
- N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(3,7-dioxo-1,9-diphenyl-2,8-dioxa-4,6-diazanonan-5-ylidene)-L-lysine (CAS 1926163-01-0)
- ACTH (4-10) (CAS 4037-01-8)
- N-(3-Phenyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5-yl)benzamide (CAS 74101-25-0)
- 3-Benzyl-1,2,4-thiadiazol-5-amine (CAS 17467-27-5)
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