N-(5-Amino-2-fluorophenyl)-2-(2-chlorophenoxy)-acetamide CAS 953739-94-1
| CAS No. | 953739-94-1 |
| Molecular Formula | C14H12ClFN2O2 |
| Molecular Weight | 294.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(5-Amino-2-fluorophenyl)-2-(2-chlorophenoxy)-acetamide (CAS 953739-94-1), molecular formula C14H12ClFN2O2 and molecular weight 294.71 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(5-Amino-2-fluorophenyl)-2-(2-chlorophenoxy)-acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12ClFN2O2 |
| Molecular Weight | 294.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- n-(5-Amino-2-methoxyphenyl)-4-chloro-2-fluorobenzamide (CAS 1016696-80-2)
- N-(5-Amino-2-chlorophenyl)-2-(3-fluorophenoxy)-acetamide (CAS 1096336-47-8)
- N-(3-Amino-4-chlorophenyl)-2-(3-fluorophenoxy)-acetamide (CAS 954575-59-8)
- N-(4-amino-2-chlorophenyl)-2-(3-fluorophenoxy)acetamide (CAS 953747-30-3)
- N-(5-Amino-2-fluorophenyl)-2-(4-chlorophenoxy)-acetamide (CAS 954271-66-0)
- 2-Amino-4-(4-chlorophenyl)thiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione (CAS 898131-77-6)
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Recommended Standards
- N-allyl-3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamide (CAS 536725-77-6)
- 6-(3-Chloro-4-fluorobenzoyl)-2-cyano-1-oxa-6-azaspiro[2.5]octane (CAS 448920-97-6)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)amino)thiazol-4(5H)-one (CAS 89335-24-0)
- 4-[(4-Fluorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 926028-22-0)
- (S)-1-Cyclopropyl-N-(4-fluorobenzyl)ethan-1-amine (CAS 1889287-64-2)
- 2-(Bromomethyl)-5-methoxypyridine hydrobromide (CAS 2007919-27-7)
- 4,5-Dimethyl-2-(2-(methylthio)ethyl)-1,3-dioxolane (CAS 59007-93-1)
- 7-Fluoroquinolin-6-amine (CAS 2102411-80-1)
- 1-(pyridine-3-sulfonyl)piperazine (CAS 26103-50-4)
- 3-Amino-1-methyl-1h-pyrazole-5-carboxamide (CAS 1129541-01-0)
- L-Homocysteine (CAS 6027-13-0)
- 3-Oxo-2-phenylprop-2-enoyl chloride (CAS 17118-70-6)
- (3R,4R)-3,4-Difluoro-1-phenylpyrrolidine (CAS 209625-77-4)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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