5-Bromo-2-chloro-N-ethylpyrimidin-4-amine CAS 954221-06-8
| CAS No. | 954221-06-8 |
| Molecular Formula | C6H7BrClN3 |
| Molecular Weight | 236.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.50 g/mol gives 5-Bromo-2-chloro-N-ethylpyrimidin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Bromo-2-chloro-N-ethylpyrimidin-4-amine (CAS 954221-06-8), molecular formula C6H7BrClN3 and molecular weight 236.50 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine/bromine substitution, an aromatic ring system, 5-Bromo-2-chloro-N-ethylpyrimidin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7BrClN3 |
| Molecular Weight | 236.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 5-Bromo-4-chloro-6-ethylpyrimidin-2-amine (CAS 1260837-10-2)
- 5-Bromo-6-chloro-N,N-dimethylpyrazin-2-amine (CAS 1379316-06-9)
- 4-Bromo-6-chloro-N-ethylpyridazin-3-amine (CAS 1396762-10-9)
- 5-Bromo-2-chloro-N4-methylpyridine-3,4-diamine (CAS 1590410-28-8)
- 5-Bromo-6-chloro-N,N-dimethylpyrimidin-4-amine (CAS 1698113-78-8)
- 5-Bromo-3-chloro-N,N-dimethylpyrazin-2-amine (CAS 1934835-77-4)
- 3-Bromo-5-chloro-N,N-dimethylpyrazin-2-amine (CAS 1936546-83-6)
- 5-Bromo-2-chloro-N,N-dimethylpyrimidin-4-amine (CAS 57054-86-1)
Recommended Standards
- 4-bromo-6-chloro-5-ethyl-3-Pyridazinamine (CAS 933035-43-9)
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- 5,7,8-Trichloro-1,2,3,4-tetrahydroisoquinoline, 98% (CAS 73075-51-1)
- Octamethyltrisiloxane (CAS 107-51-7)
- (S)-4-(2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidine 4-methylbenzenesulfonate (CAS 2401894-41-3)
- 4-Chloro-α-methoxybenzenemethanol (CAS 55685-75-1)
- N-(2-methylpentan-3-yl)cyclohexanamine (CAS 1157294-20-6)
- Amisulpride Impurity 38 (CAS 59168-56-8)
- 2-(2-Bromophenyl)pyrrolidine Oxalate (2:1) (CAS 1177278-80-6)
- 3-(2-Methoxyethyl)-2-methyl-5-phenylbenzo[d]oxazol-3-ium 4-methylbenzenesulfonate (CAS 63979-86-2)
- Tolvaptan Impurity 106 (CAS 792931-77-2)
- 3-Bromo-4-methyl-2,3-dihydrothiophene 1,1-dioxide (CAS 65017-48-3)
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