Tolvaptan Impurity 106 CAS 792931-77-2
| CAS No. | 792931-77-2 |
| Molecular Formula | C12H12ClNO3 |
| Molecular Weight | 253.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tolvaptan Impurity 106 (C12H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 253.68 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Tolvaptan Impurity 106 (CAS 792931-77-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H12ClNO3 and a molecular weight of 253.68 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tolvaptan Impurity 106 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNO3 |
| Molecular Weight | 253.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tolvaptan Standards
- Tolvaptan Impurity 37 (CAS 607-86-3)
- Tolvaptan Impurity 86 (CAS 108166-22-9)
- Tolvaptan Impurity 119 (CAS CATO-C4X-1955119)
- Tolvaptan Impurity 38 (CAS 3951-89-1)
- Tolvaptan Impurity 107 (CAS 2735310-65-1)
- Tolvaptan Impurity 5 (CAS CATO-C4X-19555)
- Tolvaptan Impurity 28 (CAS 317374-08-6)
- Tolvaptan Impurity 53 (CAS CATO-C4X-195553)
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