Perampanel Impurity 53 CAS 956229-66-6
| CAS No. | 956229-66-6 |
| Molecular Formula | C16H23BO4 |
| Molecular Weight | 290.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Perampanel Impurity 53 (CAS 956229-66-6) is a certified pharmaceutical impurity reference standard with the molecular formula C16H23BO4 and a molecular weight of 290.16 g/mol.
The molecular framework of Perampanel Impurity 53 (C16H23BO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Perampanel Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H23BO4 |
| Molecular Weight | 290.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Perampanel Standards
- Perampanel impurity 42 (CAS CATO-C4X-243042)
- Perampanel Impurity 56 (CAS CATO-C4X-243056)
- Perampanel Impurity 55 (CAS CATO-C4X-243055)
- Perampanel Impurity 57 (CAS CATO-C4X-243057)
- Perampanel Impurity 32 (CAS CATO-C4X-243032)
- Perampanel Impurity 36 (CAS CATO-C4X-243036)
- Perampanel Impurity 23 (CAS CATO-C4X-243023)
- Perampanel Impurity 7 (CAS CATO-C4X-24307)
Recommended Standards
- Bromfenac Impurity 31 (CAS 71969-36-3)
- 2-(4-Bromo-2-fluorophenoxy)-N,N-diethylethanamine (CAS 1142944-95-3)
- Propofol Impurity 49 (CAS CATO-C4X-147349)
- 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine (CAS 1150561-72-0)
- Venetoclax Impurity 129 (CAS CATO-C4X-2495129)
- Pramipexole Impurity N1 (CAS 2489686-91-9)
- Rosuvastatin Impurity 266 (CAS 775571-58-9)
- 2-(4-Bromophenyl)-1-(4-chlorophenyl)ethan-1-ol (CAS 1183175-86-1)
- 1-(((5-(4-Bromophenyl)oxazol-2-yl)methylene)amino)imidazolidine-2,4-dione (CAS 64748-79-4)
- (S)-2-methyl-1-(3,4,5-trimethoxyphenyl)propan-1-amine (CAS 1010385-31-5)
- Piperazin-1-yl(2,3,4-trimethoxyphenyl)methanone (CAS 93896-51-6)
- 2-(Prop-2-yn-1-ylamino)ethan-1-ol (CAS 28123-89-9)
- N,N-Diphenylurethane (CAS 603-52-1)
- FLAG Epitope Peptide (CAS 98849-88-8)
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