| CAS No. | CATO-C4X-147349 |
| Molecular Formula | C10H13Na2O5P |
| Molecular Weight | 290.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 290.16 g/mol gives Propofol Impurity 49 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Propofol Impurity 49 (CAS CATO-C4X-147349), a pharmacopoeial impurity reference standard (molecular formula C10H13Na2O5P, MW 290.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Propofol Impurity 49 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 290.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Propofol Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C10H13Na2O5P |
| Molecular Weight | 290.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |