Propofol Impurity 49 CAS CATO-C4X-147349

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-147349
Molecular FormulaC10H13Na2O5P
Molecular Weight290.16 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Propofol Impurity 49 CAS CATO-C4X-147349 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 290.16 g/mol gives Propofol Impurity 49 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Propofol Impurity 49 (CAS CATO-C4X-147349), a pharmacopoeial impurity reference standard (molecular formula C10H13Na2O5P, MW 290.16 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Propofol Impurity 49 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 290.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Propofol Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H13Na2O5P
Molecular Weight290.16 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present

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