4-(1-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)aniline CAS 956263-23-3
| CAS No. | 956263-23-3 |
| Molecular Formula | C16H12F3N3 |
| Molecular Weight | 303.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(1-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)aniline (CAS 956263-23-3) is a high-purity analytical reference standard with the molecular formula C16H12F3N3 and a molecular weight of 303.28 g/mol.
The molecular framework of 4-(1-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)aniline (C16H12F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3 |
| Molecular Weight | 303.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Phenyl Standards
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- 3-{4-[3-(Trifluoromethyl)pyridin-2-yl]piperazin-1-yl}propanoic acid (CAS 1155625-56-1)
- 1-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-3-((tetrahydrofuran-2-yl)methyl)urea (CAS 1858240-24-0)
- 1-(3-(Trifluoromethyl)benzyl)-1H-indole-3-carbaldehyde (CAS 192997-22-1)
- 1-Phenyl-4-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine (CAS 324008-95-9)
- 4-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)aniline (CAS 634188-12-8)
- 4-Methyl-2-[3-(trifluoromethyl)phenoxy]quinoline (CAS 338749-97-6)
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Recommended Standards
- 4-(1-Naphthyloxy)-3-(trifluoromethyl)aniline (CAS 83054-43-7)
- 4-(2-Naphthyloxy)-2-(trifluoromethyl)aniline (CAS 946784-81-2)
- 4-(1-Naphthyloxy)-2-(trifluoromethyl)aniline (CAS 212189-38-3)
- 4-(2-Naphthyloxy)-3-(trifluoromethyl)aniline (CAS 71311-90-5)
- 2,2,2-Trifluoro-1-(3-(trifluoromethyl)phenyl)ethyl trifluoromethanesulfonate (CAS 84877-49-6)
- TERT-BUTYL 4-TERT-BUTOXY-3-NITROBENZOATE (CAS 1951440-96-2)
- 3-Bromo-1-(trifluoromethyl)-1H-pyrazole (CAS 2092804-01-6)
- 1-Benzyl-2-(ethylthio)-1H-imidazole-5-carbaldehyde (CAS 479400-31-2)
- Rel-tert-butyl (((1R,3R)-3-aminocyclohexyl)methyl)carbamate hydrochloride (CAS 2095192-30-4)
- 3-(4-Chloro-2-methylphenyl)pentan-3-ol (CAS 1379367-52-8)
- 4-(Dichloro(methyl)silyl)butanenitrile (CAS 1190-16-5)
- 5-Bromo-2-iodo-3-methoxypyrazine (CAS 476622-89-6)
- 2,4-Decadien-1-ol (CAS 18409-21-7)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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