2-(2-Methoxyphenoxy)-N-(2-oxotetrahydrothiophen-3-yl)nicotinamide CAS 956355-59-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Methoxyphenoxy)-N-(2-oxotetrahydrothiophen-3-yl)nicotinamide.

2-(2-Methoxyphenoxy)-N-(2-oxotetrahydrothiophen-3-yl)nicotinamide (CAS 956355-59-2), molecular formula C17H16N2O4S and molecular weight 344.38 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(2-Methoxyphenoxy)-N-(2-oxotetrahydrothiophen-3-yl)nicotinamide (C17H16N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2-Methoxyphenoxy)-N-(2-oxotetrahydrothiophen-3-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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