4-Methoxy-N-((1-methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)benzamide CAS 956753-95-0
| CAS No. | 956753-95-0 |
| Molecular Formula | C20H18F3N3O3 |
| Molecular Weight | 405.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 405.37 g/mol gives 4-Methoxy-N-((1-methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Methoxy-N-((1-methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)benzamide (CAS 956753-95-0), molecular formula C20H18F3N3O3 and molecular weight 405.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Methoxy-N-((1-methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)benzamide (C20H18F3N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18F3N3O3 |
| Molecular Weight | 405.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)acetic acid (CAS 2137462-64-5)
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- 1-(Diphenylphosphoryl)-N-(4-(trifluoromethyl)phenyl)methanethioamide (CAS 680213-01-8)
- N-Nitroso Nafamostat impurity 117 (CAS CATO-C4X-1332117)
- 2-Phenylpyrazolo[1,5-c]quinazolin-5(6H)-one (CAS 178114-20-0)
- 3-(Sec-butoxy)benzaldehyde (CAS 915924-09-3)
- (S)-2-Amino-3-(2,3-dimethylphenyl)propan-1-ol (CAS 2349513-25-1)
- CHDI 00390576 (CAS 1629729-98-1)
- 7-Bromobenzo[d]isoxazol-3-amine (CAS 1260860-32-9)
- Ethyl 4-Cyclopropylthiazole-2-carboxylate (CAS 439692-05-4)
- 4-Cyclopropoxy-2-fluoro-1-isopropylbenzene (CAS 1243472-03-8)
- Methyl 2-chloro-5-nitrophenylacetate (CAS 219712-63-7)
- Lincomycin Hydrochloride Impurity B (Mixture of Diastereomers) (CAS CATO-C4X-13424)
- Exenatide (CAS 141758-74-9（free base）)
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