2-(7-Fluorobenzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 958451-92-8
| CAS No. | 958451-92-8 |
| Molecular Formula | C14H16BFO2S |
| Molecular Weight | 278.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(7-Fluorobenzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
CATO supplies 2-(7-Fluorobenzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 958451-92-8), a certified reference material (molecular formula C14H16BFO2S, MW 278.15 g/mol) for analytical method development and quality control.
The molecular framework of 2-(7-Fluorobenzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C14H16BFO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16BFO2S |
| Molecular Weight | 278.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluorobenzo Standards
- 2-(6-Fluorobenzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1381960-83-3)
- N-(6-Fluorobenzo[d]thiazol-2-yl)-5-methylisoxazole-3-carboxamide (CAS 930919-58-7)
- Methyl 5-(5-fluorobenzo[b]thiophen-2-yl)-1H-pyrrole-2-carboxylate (CAS 2113652-82-5)
- N-(6-Fluorobenzo[d]thiazol-2-yl)benzamide (CAS 16194-65-3)
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- S-(2-((6-Fluorobenzo[d]thiazol-2-yl)amino)-2-oxoethyl) ethanethioate (CAS 955715-09-0)
- N-(4-Fluorobenzo[d]thiazol-2-yl)-2-phenylacetamide (CAS 907974-83-8)
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Recommended Standards
- 2-(5-(Methoxymethoxy)-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2470916-94-8)
- 2-(8-Ethynylnaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2229969-04-2)
- 2-(4-(Dimethoxymethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 943239-68-7)
- 2-amino-3-bromo-1,7-naphthyridine-6-carboxylic acid (CAS 2691878-65-4)
- 3,3-Difluoro-1-(4-methoxyphenyl)-4-phenylazetidin-2-one (CAS 171251-50-6)
- Iodotris(triphenylphosphine)copper (CAS 15709-82-7)
- N-(piperidin-4-yl)pyridin-3-amine dihydrochloride (CAS 1010827-02-7)
- 2-Amino-4,7-dihydro-5H-spiro[benzo[b]thiophene-6,2'-[1,3]dioxolane]-3-carboxamide (CAS 848324-27-6)
- Funapide (CAS 1259933-16-8)
- 2-(4-amino-3-methylbenzenesulfonyl)ethan-1-ol (CAS 1566347-08-7)
- Tocopherol impurity 40 (CAS CATO-C4X-119540)
- Lornoxicam Impurity 7 (CAS 187746-94-7)
- 2-(4-Oxazol-2-yl-benzenesulfonylamino)-3-({1-[3-(pyridin-2-ylamino)-propyl]-1H-indazole-5-carbonyl}-amino)-propionic acid (CAS 1231017-67-6)
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