4-Chloro-5-ethyl-2-methylpyrimidine CAS 959239-71-5
| CAS No. | 959239-71-5 |
| Molecular Formula | C7H9ClN2 |
| Molecular Weight | 156.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-5-ethyl-2-methylpyrimidine is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloro-5-ethyl-2-methylpyrimidine (CAS 959239-71-5), a certified reference material (molecular formula C7H9ClN2, MW 156.61 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-5-ethyl-2-methylpyrimidine (C7H9ClN2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9ClN2 |
| Molecular Weight | 156.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-2-phenylethanol (CAS 1004-99-5)
- 6-Chloro-5-ethylpyridin-2-amine (CAS 1004294-54-5)
- 4-Chloro-5-isopropylpyrimidine (CAS 1015846-32-8)
- 6-chloro-1-N-methylbenzene-1,2-diamine (CAS 102074-47-5)
- 2-chloro-3,4-dimethylphenol (CAS 10283-15-5)
- 2-Chloro-4,5,6,7-tetrahydro-1H-benzimidazole (CAS 1049127-52-7)
- 3-Chloro-N,N-dimethylpyridin-2-amine (CAS 1060801-41-3)
- 6-Chloro-N,N-dimethylpyridin-2-amine (CAS 1060801-42-4)
Recommended Standards
- 4-Chloro-3-methyl-o-phenylenediamine (CAS 673487-36-0)
- 4-Chloro-5-ethyl-6-methylpyrimidine (CAS 67434-67-7)
- 4-Chloro-3,5,6-trimethylpyridazine (CAS 24307-79-7)
- 4-Chloro-5-methylbenzene-1,2-diamine (CAS 63155-04-4)
- Platinum,[μ-[N,N'-bis[3-(amino-κN)propyl]-1,4-butanediamine-κN:κN']]bis[propanedioato(2-)-κO1,κO3]di- (CAS 187224-64-2)
- 5-(Morpholine-4-sulfonyl)-2-phenoxyaniline (CAS 736948-90-6)
- Methyl 6-chloro-1-oxoisochromane-3-carboxylate (CAS 951896-50-7)
- N-(4-aminocyclohexyl)hexanamide hydrochloride (CAS 1587534-37-9)
- 3-(6-Bromo-3-indolyl)propanoic Acid (CAS 210569-69-0)
- 2-(4-bromophenyl)-2-methylpropan-1-amine (CAS 264602-70-2)
- 4-Chloro-5-methyl-2-(methylthio)-7H-pyrrolo[2,3-d]pyrimidine (CAS 64609-32-1)
- 5-Chloro-3-(2,2,2-trifluoroethoxy)thiophene-2-carboxylic acid (CAS 1774902-56-5)
- 1-(2,3-Dimethylphenyl)-5-phenyl-4,5-dihydro-1h-pyrazole-3-carboxylic acid (CAS 1264044-14-5)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
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