Sildenafil Impurity 71 CAS 960009-35-2
| CAS No. | 960009-35-2 |
| Molecular Formula | C12H16N2O5S |
| Molecular Weight | 300.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Sildenafil Impurity 71 (C12H16N2O5S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Sildenafil Impurity 71 (CAS 960009-35-2, C12H16N2O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sildenafil Impurity 71 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O5S |
| Molecular Weight | 300.33 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 248 (CAS 139756-30-2)
- Sildenafil Impurity 92 (CAS CATO-C4X-112892)
- Sildenafil Impurity 31 (CAS CATO-C4X-112831)
- Sildenafil Impurity 2 (CAS 332374-42-2)
- Sildenafil Impurity 299 (CAS CATO-C4X-1128299)
- Sildenafil Impurity 69 (CAS CATO-C4X-112869)
- Sildenafil Impurity 77 (CAS CATO-C4X-112877)
- Sildenafil Impurity 28 (CAS 139756-26-6)
Recommended Standards
- 4-[4-(ethanesulfonyl)-2-nitrophenyl]morpholine 5-(Ethylsulphonyl)-2-(morpholin-4-yl)nitrobenzene 942474-41-1 Ethyl 4-(morpholin-4-yl)-3-nitrophenyl sulphone (CAS 942474-41-1)
- Safinamide Impurity 22 (CAS 1000370-31-9)
- Oleic acid-13C18 (CAS 287100-82-7)
- Safinamide impurity 50 (CAS CATO-C4X-159050)
- Upadacitinib Impurity 57 (CAS CATO-C4X-240557)
- Dapagliflozin Impurity 8 (CAS 1662702-90-0)
- Citalopram EP Impurity A (CAS 64372-56-1)
- (R)-2-(3-methyl-2-(trifluoromethyl)phenyl)pyrrolidine (CAS 1389352-34-4)
- 5-Bromo-2-(methylthio)pyrimidine-4-methanol (CAS 944317-70-8)
- 1-(2-Ethoxyphenyl)-1H-pyrrole-2-carboxylic acid (CAS 896035-81-7)
- 2-(3-Bromo-5-fluoro-4-isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621936-40-9)
- cis-Calamenene (CAS 72937-55-4)
- Tert-butyl 4-(aminomethyl)-4-fluoroazepane-1-carboxylate (CAS 1824467-83-5)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com